Abstract
The CCCH class of zinc fingers occurs in a large number of Arabidopsis proteins. Previous studies revealed that one such protein is a nuclease, the activity of which is attributable to one of the CCCH motifs. To examine whether nuclease activity is a more general characteristic of CCCH zinc finger containing proteins, five other such Arabidopsis proteins were assayed for a similar activity. The results indicate that all of these proteins possess nuclease activity. Thus, nuclease activity may be a common characteristic of Arabidopsis CCCH-containing proteins.
| Original language | English |
|---|---|
| Pages (from-to) | 2577-2582 |
| Number of pages | 6 |
| Journal | FEBS Letters |
| Volume | 582 |
| Issue number | 17 |
| DOIs | |
| State | Published - Jul 23 2008 |
Bibliographical note
Funding Information:The authors thank Carol Von Lanken for excellent technical and administrative support. This work was supported by NSF Arabidopsis 2010 Grant MCB-0313472.
Funding
The authors thank Carol Von Lanken for excellent technical and administrative support. This work was supported by NSF Arabidopsis 2010 Grant MCB-0313472.
| Funders | Funder number |
|---|---|
| U.S. Department of Energy Chinese Academy of Sciences Guangzhou Municipal Science and Technology Project Oak Ridge National Laboratory Extreme Science and Engineering Discovery Environment National Science Foundation National Energy Research Scientific Computing Center National Natural Science Foundation of China | MCB-0313472 |
Keywords
- Polyadenylation
- RNA binding
- Ribonuclease
- Zinc-finger protein
ASJC Scopus subject areas
- Biophysics
- Structural Biology
- Biochemistry
- Molecular Biology
- Genetics
- Cell Biology