Abstract
This case report further establishes the inhibitory effects of paroxetine on risperidone (R) metabolism in a patient whose R was discontinued due to side effects. Baseline through levels in ng/ml were 33 for R, 9 for 9-hydroxyrisperidone (9-OHR) and 42 for the total moiety. The fourth morning after R discontinuation, levels were 4 for R, 1 for 9-OHR and 5 for the total moiety. The estimated half-lives were 23.8 hours for R, 22.8 hours for 9-OHR and 23.5 hours for the total moiety.
Original language | English |
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Pages (from-to) | 223-225 |
Number of pages | 3 |
Journal | Pharmacopsychiatry |
Volume | 38 |
Issue number | 5 |
DOIs | |
State | Published - Sep 2005 |
ASJC Scopus subject areas
- Psychiatry and Mental health
- Pharmacology (medical)