Hemagglutinin inhibition antibody responses to commercial equine influenza vaccines in vaccinated horses

Translated title of the contribution: Hemagglutinin inhibition antibody responses to commercial equine influenza vaccines in vaccinated horses

Bruno Karam, William D. Wilson, Thomas M. Chambers, Stephanie Reedy, Nicola Pusterla

Research output: Contribution to journalArticlepeer-review

Abstract

The use of a hemagglutination inhibition (HI) assay to assess humoral immune response to equine influenza virus (EIV) vaccines from various manufacturers administered to previously immunized adult horses was investigated. Subjects were allocated into one of 3 groups and vaccinated with various commercially available vaccines. Groups were subdivided into subjects that received i dose of a particular vaccine and those that received a second dose, 30 d later. Serum was collected at various times to assess antibody responses to contemporary EIV Florida sub-lineage strains. Statistical significance was set at P < 0.05 and all groups had a significant increase in antibody titers pre- A nd post-administration of the first dose. In contrast, there was no significant difference between day 30 titers and titers at subsequent time points, regardless of protocol. We concluded that administration of various commercial influenza vaccines containing a difFerent sub-lineage clade stimulated equivalent HI antibody titers after 1 booster vaccination.

Translated title of the contributionHemagglutinin inhibition antibody responses to commercial equine influenza vaccines in vaccinated horses
Original languageEnglish
Pages (from-to)266-272
Number of pages7
JournalCanadian Veterinary Journal
Volume62
Issue number3
StatePublished - Mar 2021

Bibliographical note

Publisher Copyright:
© 2021 Canadian Veterinary Medical Association. All rights reserved.

ASJC Scopus subject areas

  • General Medicine

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