RNA interference in Colorado potato beetle: Steps toward development of dsRNA as a commercial insecticide

Subba Reddy Palli

doi:10.1016/j.cois.2014.09.011

RNA interference in Colorado potato beetle: Steps toward development of dsRNA as a commercial insecticide

Subba Reddy Palli

Research output: Contribution to journal › Review article › peer-review

145 Citations (SciVal)

Abstract

Colorado potato beetle (CPB) is a notorious pest on potatoes and has a remarkable ability to detoxify plant chemicals and develop resistance against insecticides. dsRNA targeting CPB genes could be expressed in potato plants to control this pest. However, previous attempts at introducing transgenic potato plants to control CPB were not highly successful. Recent studies showed that feeding dsRNA expressed in bacteria works very well to kill CPB. To realize the potential of RNAi to control this and other economically important pests, more efficient methods for production and delivery of dsRNA need to be developed. Extensive research to determine off-target and non-target effects, environmental fate and potential for resistance development is also essential.

Original language	English
Pages (from-to)	1-8
Number of pages	8
Journal	Current Opinion in Insect Science
Volume	6
DOIs	https://doi.org/10.1016/j.cois.2014.09.011
State	Published - Dec 2014

Bibliographical note

Publisher Copyright:
© 2014 Elsevier Inc.

ASJC Scopus subject areas

Ecology, Evolution, Behavior and Systematics
Insect Science

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10.1016/j.cois.2014.09.011

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title = "RNA interference in Colorado potato beetle: Steps toward development of dsRNA as a commercial insecticide",

abstract = "Colorado potato beetle (CPB) is a notorious pest on potatoes and has a remarkable ability to detoxify plant chemicals and develop resistance against insecticides. dsRNA targeting CPB genes could be expressed in potato plants to control this pest. However, previous attempts at introducing transgenic potato plants to control CPB were not highly successful. Recent studies showed that feeding dsRNA expressed in bacteria works very well to kill CPB. To realize the potential of RNAi to control this and other economically important pests, more efficient methods for production and delivery of dsRNA need to be developed. Extensive research to determine off-target and non-target effects, environmental fate and potential for resistance development is also essential.",

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doi = "10.1016/j.cois.2014.09.011",

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N2 - Colorado potato beetle (CPB) is a notorious pest on potatoes and has a remarkable ability to detoxify plant chemicals and develop resistance against insecticides. dsRNA targeting CPB genes could be expressed in potato plants to control this pest. However, previous attempts at introducing transgenic potato plants to control CPB were not highly successful. Recent studies showed that feeding dsRNA expressed in bacteria works very well to kill CPB. To realize the potential of RNAi to control this and other economically important pests, more efficient methods for production and delivery of dsRNA need to be developed. Extensive research to determine off-target and non-target effects, environmental fate and potential for resistance development is also essential.

AB - Colorado potato beetle (CPB) is a notorious pest on potatoes and has a remarkable ability to detoxify plant chemicals and develop resistance against insecticides. dsRNA targeting CPB genes could be expressed in potato plants to control this pest. However, previous attempts at introducing transgenic potato plants to control CPB were not highly successful. Recent studies showed that feeding dsRNA expressed in bacteria works very well to kill CPB. To realize the potential of RNAi to control this and other economically important pests, more efficient methods for production and delivery of dsRNA need to be developed. Extensive research to determine off-target and non-target effects, environmental fate and potential for resistance development is also essential.

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DO - 10.1016/j.cois.2014.09.011

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AN - SCOPUS:84923827965

SN - 2214-5745

VL - 6

SP - 1

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JO - Current Opinion in Insect Science

JF - Current Opinion in Insect Science

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RNA interference in Colorado potato beetle: Steps toward development of dsRNA as a commercial insecticide

Abstract

Bibliographical note

ASJC Scopus subject areas

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