Robust in vitro activity of RebF and RebH, a two-component reductase/halogenase, generating 7-chlorotryptophan during rebeccamycin biosynthesis

Chemistry

• 7-Chlorotryptophan 100%
• Rebeccamycin 100%
• Biosynthesis 100%
• FADH2 66%
• Rate 33%
• Catalysis 33%
• Reduction 33%
• Antineoplastic Agent 33%
• Halogen 33%
• Kcat 33%
• NADH 33%
• Chloride Ion 33%
• Saturated Solution 33%
• Flavin 33%
• Chlorine Atom 33%
• Indolocarbazole 33%
• Indole 33%
• Ion 33%
• Natural Product 33%
• halogenation 33%
• catalytic cycle 33%

Biochemistry, Genetics and Molecular Biology

• Anabolism 100%
• Reductase 100%
• Oxidoreductase 100%
• Enzyme 66%
• Reduction (Chemistry) 33%
• Solution and Solubility 33%
• Atom 33%
• Catalysis 33%
• Bromide 33%
• Flavin Reductase 33%
• Gene 33%
• Halogenation 33%
• Turnover Number 33%
• Oxygen Tension 33%
• Aglycone 33%
• Chloride 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Rebeccamycin 100%
• Oxidoreductase 100%
• Enzymes 100%
• Aglycone 50%
• Indole 50%
• Riboflavin Derivative 50%
• Anticarcinogen 50%
• Natural Product 50%
• Chloride Ion 50%
• Chlorine 50%
• Halogen 50%
• Bromide Ion 50%