Role of microRNAs in diabetes

Xiaoqing Tang; Guiliang Tang; Sabire Özcan

doi:10.1016/j.bbagrm.2008.06.010

Role of microRNAs in diabetes

Xiaoqing Tang, Guiliang Tang, Sabire Özcan

Molecular and Cellular Biochemistry

Research output: Contribution to journal › Review article › peer-review

153 Scopus citations

Abstract

Diabetes is one of the most common chronic diseases in the world. Multiple and complex factors including various genetic and physiological changes can lead to type 1 and type 2 diabetes. However, the major mechanisms underlying the pathogenesis of diabetes remain obscure. With the recent discovery of microRNAs (miRNAs), these small ribonucleotides have been implicated as new players in the pathogenesis of diabetes and diabetes-associated complications. MiRNAs have been shown to regulate insulin production, insulin secretion, and insulin action. This review summarizes the recent progress in the cutting-edge research of miRNAs involved in diabetes and diabetes related complications.

Original language	English
Pages (from-to)	697-701
Number of pages	5
Journal	Biochimica et Biophysica Acta - Gene Regulatory Mechanisms
Volume	1779
Issue number	11
DOIs	https://doi.org/10.1016/j.bbagrm.2008.06.010
State	Published - Nov 2008

Keywords

Diabetes
Diabetic complication
Insulin
MiRNA
Pancreas

ASJC Scopus subject areas

Biophysics
Structural Biology
Biochemistry
Molecular Biology
Genetics

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.bbagrm.2008.06.010

Cite this

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title = "Role of microRNAs in diabetes",

abstract = "Diabetes is one of the most common chronic diseases in the world. Multiple and complex factors including various genetic and physiological changes can lead to type 1 and type 2 diabetes. However, the major mechanisms underlying the pathogenesis of diabetes remain obscure. With the recent discovery of microRNAs (miRNAs), these small ribonucleotides have been implicated as new players in the pathogenesis of diabetes and diabetes-associated complications. MiRNAs have been shown to regulate insulin production, insulin secretion, and insulin action. This review summarizes the recent progress in the cutting-edge research of miRNAs involved in diabetes and diabetes related complications.",

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AU - Tang, Guiliang

AU - Özcan, Sabire

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AB - Diabetes is one of the most common chronic diseases in the world. Multiple and complex factors including various genetic and physiological changes can lead to type 1 and type 2 diabetes. However, the major mechanisms underlying the pathogenesis of diabetes remain obscure. With the recent discovery of microRNAs (miRNAs), these small ribonucleotides have been implicated as new players in the pathogenesis of diabetes and diabetes-associated complications. MiRNAs have been shown to regulate insulin production, insulin secretion, and insulin action. This review summarizes the recent progress in the cutting-edge research of miRNAs involved in diabetes and diabetes related complications.

KW - Diabetes

KW - Diabetic complication

KW - Insulin

KW - MiRNA

KW - Pancreas

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DO - 10.1016/j.bbagrm.2008.06.010

M3 - Review article

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AN - SCOPUS:55049097738

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JO - Biochimica et Biophysica Acta - Gene Regulatory Mechanisms

JF - Biochimica et Biophysica Acta - Gene Regulatory Mechanisms

IS - 11

ER -

Role of microRNAs in diabetes

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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