Role of microRNAs in diabetes

Xiaoqing Tang, Guiliang Tang, Sabire Özcan

Research output: Contribution to journalReview articlepeer-review

142 Scopus citations


Diabetes is one of the most common chronic diseases in the world. Multiple and complex factors including various genetic and physiological changes can lead to type 1 and type 2 diabetes. However, the major mechanisms underlying the pathogenesis of diabetes remain obscure. With the recent discovery of microRNAs (miRNAs), these small ribonucleotides have been implicated as new players in the pathogenesis of diabetes and diabetes-associated complications. MiRNAs have been shown to regulate insulin production, insulin secretion, and insulin action. This review summarizes the recent progress in the cutting-edge research of miRNAs involved in diabetes and diabetes related complications.

Original languageEnglish
Pages (from-to)697-701
Number of pages5
JournalBiochimica et Biophysica Acta - Gene Regulatory Mechanisms
Issue number11
StatePublished - Nov 2008


  • Diabetes
  • Diabetic complication
  • Insulin
  • MiRNA
  • Pancreas

ASJC Scopus subject areas

  • Biophysics
  • Structural Biology
  • Biochemistry
  • Molecular Biology
  • Genetics


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