During normal fetal development, a balance between the production of oxidants and the antioxidant defense systems is critical for proper growth and development. Studies have shown that an imbalance between oxidant production and antioxidant defense mechanisms may lead to preterm birth, fetal growth restriction, and related morbidities. Premature infants are highly susceptible to oxidant-induced damage due to immature antioxidant defense systems or deficiency of antioxidants. As a result there is an increased risk for the development of oxidant-induced diseases of the newborn, such as bronchopulmonary dysplasia, retinopathy of prematurity, and periventricular leukomalacia.
|Title of host publication||Gastrointestinal Tissue|
|Subtitle of host publication||Oxidative Stress and Dietary Antioxidants|
|Number of pages||12|
|State||Published - Jan 1 2017|
- Necrotizing enterocolitis
ASJC Scopus subject areas
- Medicine (all)