Role of reaction kinetics and mass transport in glucose sensing with nanopillar array electrodes

Venkataramani Anandan, Xiaoling Yang, Euihyeon Kim, Yeswanth L. Rao, Guigen Zhang

Research output: Contribution to journalArticlepeer-review

32 Scopus citations

Abstract

The use of nanopillar array electrodes (NAEs) for biosensor applications was explored using a combined experimental and simulation approach to characterize the role of reaction kinetics and mass transport in glucose detection with NAEs. Thin gold electrodes with arrays of vertically standing gold nanopillars were fabricated and their amperometric current responses were measured under bare and functionalized conditions. Results show that the sensing performances of both the bare and functionalized NAEs were affected not only by the presence and variation of the nanoscale structures on the electrodes but also by the reaction kinetics and mass transport of the analyte species involved. These results will shed new light for enhancing the performance of nanostructure based biosensors.

Original languageEnglish
Article number5
JournalJournal of Biological Engineering
Volume1
DOIs
StatePublished - Oct 10 2007

ASJC Scopus subject areas

  • Environmental Engineering
  • Biomedical Engineering
  • Molecular Biology
  • Cell Biology

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