Sample size calculation for the one-sample log-rank test

Jianrong Wu

Research output: Contribution to journalArticlepeer-review

37 Scopus citations


In this paper, an exact variance of the one-sample log-rank test statistic is derived under the alternative hypothesis, and a sample size formula is proposed based on the derived exact variance. Simulation results showed that the proposed sample size formula provides adequate power to design a study to compare the survival of a single sample with that of a standard population.

Original languageEnglish
Pages (from-to)26-33
Number of pages8
JournalPharmaceutical Statistics
Issue number1
StatePublished - Jan 1 2015

Bibliographical note

Publisher Copyright:
Copyright © 2014 JohnWiley & Sons, Ltd.


  • Counting process
  • One-sample log-rank test
  • Sample size formula
  • Standard population
  • Time to event

ASJC Scopus subject areas

  • Statistics and Probability
  • Pharmacology
  • Pharmacology (medical)


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