Schizophrenia and tobacco smoking in a Spanish psychiatric hospital

Adrián Llerena, Alfredo De La Rubia, Eva M. Peñas-Lledó, Francisco J. Diaz, Jose De Leon

Research output: Contribution to journalComment/debate

42 Scopus citations


This study in a Spanish hospital replicated two US studies suggesting that schizophrenia is associated with smoking when compared with other severe mental illnesses. Neither antipsychotics nor institutionalism could explain this relationship. Seventy of the 100 schizophrenic and 53 of the 100 non-schizophrenic inpatients were current smokers. After correcting for confounding factors, schizophrenia increased the risk of smoking by 2- to 3-fold. Heavy smoking was not associated with schizophrenia.

Original languageEnglish
Pages (from-to)313-317
Number of pages5
JournalSchizophrenia Research
Issue number2-3
StatePublished - Apr 1 2003

Bibliographical note

Funding Information:
The authors are grateful to the patients and staff from the Merida Psychiatric Hospital for their collaboration. This study was possible by a grant awarded to Dr. LLerena from the Government of Extramadura (Junta de Extremadura, Consejeria de Educación Ciencia y Tecnologı́a y Fondo Social Europeo IPRI0036). Dr. de Leon's salary was partly supported by grants MH-51380 from the National Institute of Mental Health. Francisco Diaz is an Associate Instructor in Statistics at Universidad Nacional de Colombia and was supported by a grant from the Kentucky Department of Mental Health and Mental Retardation and the Department of Psychiatry of the University of Kentucky through the University Collaboration Project, and by a fellowship from the Department of Statistics of the University of Kentucky.


  • Antipsychotics
  • Logistics regression
  • Schizophrenia
  • Smoking
  • Tobacco

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry


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