Schizophrenic syndrome and Wisconsin Card Sorting Test dimensions

Manuel J. Cuesta; Victor Peralta; Francisco Caro; Jose de Leon

doi:10.1016/0165-1781(95)02649-H

Schizophrenic syndrome and Wisconsin Card Sorting Test dimensions

Manuel J. Cuesta
, Victor Peralta
, Francisco Caro
, Jose de Leon

Research output: Contribution to journal › Article › peer-review

52 Scopus citations

Abstract

A principal component analysis of Wisconsin Card Sorting Test (WCST) scores has recently shown three factors. Only the Perseveration factor may measure the activity of the dorsolateral prefrontal cortex in schizophrenic patients. Liddle has hypothesized that a dysfunction in this area is specifically related to the negative syndrome and not to other schizophrenic syndromes (positive and disorganization). The factor analysis of the WCST was replicated with similar results in 38 schizophrenic or schizoaffective patients. In the total group, the correlation between the negative syndrome and the Perseveration factor did not reach significant levels. In the patients with a DSM-III-R diagnosis of schizophrenia (n = 30), the correlations did reach significant levels.

Original language	English
Pages (from-to)	45-51
Number of pages	7
Journal	Psychiatry Research
Volume	58
Issue number	1
DOIs	https://doi.org/10.1016/0165-1781(95)02649-H
State	Published - Sep 8 1995

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Factor analysis
Frontal lobe
Neuropsychology
Positive and negative symptoms of schizophrenia
Schizoaffective disorder

ASJC Scopus subject areas

Psychiatry and Mental health
Biological Psychiatry

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10.1016/0165-1781(95)02649-H

Cite this

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abstract = "A principal component analysis of Wisconsin Card Sorting Test (WCST) scores has recently shown three factors. Only the Perseveration factor may measure the activity of the dorsolateral prefrontal cortex in schizophrenic patients. Liddle has hypothesized that a dysfunction in this area is specifically related to the negative syndrome and not to other schizophrenic syndromes (positive and disorganization). The factor analysis of the WCST was replicated with similar results in 38 schizophrenic or schizoaffective patients. In the total group, the correlation between the negative syndrome and the Perseveration factor did not reach significant levels. In the patients with a DSM-III-R diagnosis of schizophrenia (n = 30), the correlations did reach significant levels.",

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AU - Cuesta, Manuel J.

AU - Peralta, Victor

AU - Caro, Francisco

AU - de Leon, Jose

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N2 - A principal component analysis of Wisconsin Card Sorting Test (WCST) scores has recently shown three factors. Only the Perseveration factor may measure the activity of the dorsolateral prefrontal cortex in schizophrenic patients. Liddle has hypothesized that a dysfunction in this area is specifically related to the negative syndrome and not to other schizophrenic syndromes (positive and disorganization). The factor analysis of the WCST was replicated with similar results in 38 schizophrenic or schizoaffective patients. In the total group, the correlation between the negative syndrome and the Perseveration factor did not reach significant levels. In the patients with a DSM-III-R diagnosis of schizophrenia (n = 30), the correlations did reach significant levels.

AB - A principal component analysis of Wisconsin Card Sorting Test (WCST) scores has recently shown three factors. Only the Perseveration factor may measure the activity of the dorsolateral prefrontal cortex in schizophrenic patients. Liddle has hypothesized that a dysfunction in this area is specifically related to the negative syndrome and not to other schizophrenic syndromes (positive and disorganization). The factor analysis of the WCST was replicated with similar results in 38 schizophrenic or schizoaffective patients. In the total group, the correlation between the negative syndrome and the Perseveration factor did not reach significant levels. In the patients with a DSM-III-R diagnosis of schizophrenia (n = 30), the correlations did reach significant levels.

KW - Factor analysis

KW - Frontal lobe

KW - Neuropsychology

KW - Positive and negative symptoms of schizophrenia

KW - Schizoaffective disorder

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Schizophrenic syndrome and Wisconsin Card Sorting Test dimensions

Abstract

UN SDGs

Keywords

ASJC Scopus subject areas

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