Scintillation proximity radioimmunoassay with microporous membranes

Robert K. Mansfield, Dibakar Bhattacharyya, Neil G. Hartman, Michael Jay

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Fluors were incorporated into the matrix of microporous polymeric membranes and antibodies were subsequently bound to their surfaces. These membranes were used in competitive binding assays (secondary RIAs) for cyclic-AMP in which the bound and unbound radioligands did not require separation. Membrane-based scintillation proximity assays have utility for the detection of a variety of radioanalytes and can be configured in a number of sizes and shapes.

Original languageEnglish
Pages (from-to)323-328
Number of pages6
JournalApplied Radiation and Isotopes
Issue number3
StatePublished - Mar 1996

Bibliographical note

Funding Information:
Acknowledgements--This work was supported in part by NSF Grant EHR-9108764 and the Kentucky EPSCoR Program.

ASJC Scopus subject areas

  • Radiation


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