Scintillation proximity radioimmunoassay with microporous membranes

Robert K. Mansfield; Dibakar Bhattacharyya; Neil G. Hartman; Michael Jay

doi:10.1016/0969-8043(95)00299-5

Scintillation proximity radioimmunoassay with microporous membranes

Robert K. Mansfield, Dibakar Bhattacharyya, Neil G. Hartman, Michael Jay

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Fluors were incorporated into the matrix of microporous polymeric membranes and antibodies were subsequently bound to their surfaces. These membranes were used in competitive binding assays (secondary RIAs) for cyclic-AMP in which the bound and unbound radioligands did not require separation. Membrane-based scintillation proximity assays have utility for the detection of a variety of radioanalytes and can be configured in a number of sizes and shapes.

Original language	English
Pages (from-to)	323-328
Number of pages	6
Journal	Applied Radiation and Isotopes
Volume	47
Issue number	3
DOIs	https://doi.org/10.1016/0969-8043(95)00299-5
State	Published - Mar 1996

Bibliographical note

Funding Information:
Acknowledgements--This work was supported in part by NSF Grant EHR-9108764 and the Kentucky EPSCoR Program.

ASJC Scopus subject areas

Radiation

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10.1016/0969-8043(95)00299-5

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title = "Scintillation proximity radioimmunoassay with microporous membranes",

abstract = "Fluors were incorporated into the matrix of microporous polymeric membranes and antibodies were subsequently bound to their surfaces. These membranes were used in competitive binding assays (secondary RIAs) for cyclic-AMP in which the bound and unbound radioligands did not require separation. Membrane-based scintillation proximity assays have utility for the detection of a variety of radioanalytes and can be configured in a number of sizes and shapes.",

author = "Mansfield, {Robert K.} and Dibakar Bhattacharyya and Hartman, {Neil G.} and Michael Jay",

note = "Funding Information: Acknowledgements--This work was supported in part by NSF Grant EHR-9108764 and the Kentucky EPSCoR Program.",

year = "1996",

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doi = "10.1016/0969-8043(95)00299-5",

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AU - Mansfield, Robert K.

AU - Bhattacharyya, Dibakar

AU - Hartman, Neil G.

AU - Jay, Michael

N1 - Funding Information: Acknowledgements--This work was supported in part by NSF Grant EHR-9108764 and the Kentucky EPSCoR Program.

PY - 1996/3

Y1 - 1996/3

N2 - Fluors were incorporated into the matrix of microporous polymeric membranes and antibodies were subsequently bound to their surfaces. These membranes were used in competitive binding assays (secondary RIAs) for cyclic-AMP in which the bound and unbound radioligands did not require separation. Membrane-based scintillation proximity assays have utility for the detection of a variety of radioanalytes and can be configured in a number of sizes and shapes.

AB - Fluors were incorporated into the matrix of microporous polymeric membranes and antibodies were subsequently bound to their surfaces. These membranes were used in competitive binding assays (secondary RIAs) for cyclic-AMP in which the bound and unbound radioligands did not require separation. Membrane-based scintillation proximity assays have utility for the detection of a variety of radioanalytes and can be configured in a number of sizes and shapes.

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JO - Applied Radiation and Isotopes

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IS - 3

ER -

Scintillation proximity radioimmunoassay with microporous membranes

Abstract

Bibliographical note

ASJC Scopus subject areas

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