Screening of marine Streptomyces with antibacterial activity from JiaoZhou bay and studies on metabolites from strain M097

Hong Xia Cui; Song Qin; Khaled Shaaban; Harmut Laatsch

Screening of marine Streptomyces with antibacterial activity from JiaoZhou bay and studies on metabolites from strain M097

Hong Xia Cui, Song Qin, Khaled Shaaban, Harmut Laatsch

Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Aim: To get inhibitory bacteria compounds from marine Streptomyces. Method: Using 8 test strains, 256 Streptomyces from ocean were screened with their activities against bacteria. Strain M097 was selected to get an optimum condition. Active compounds have been isolated from the crude extraction by fermentation, ethyl acetate extraction, column chromatography etc. Result: The proportion of active marine streptomyces was 22%. 3 compounds produced by marine Streptomyces M097 were identified as feigrisolides A, B and C respectively. Conclusion: Marine Streptomycetes showed promising prospects in discovery of inhibitory bacterial substances.

Original language	English
Pages (from-to)	308-311
Number of pages	4
Journal	Chinese Journal of Natural Medicines
Volume	4
Issue number	4
State	Published - Jul 2006

Keywords

Active metabolites
M097
Marine Streptomyces
Test strain

ASJC Scopus subject areas

Drug Discovery
Complementary and alternative medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "Screening of marine Streptomyces with antibacterial activity from JiaoZhou bay and studies on metabolites from strain M097",

abstract = "Aim: To get inhibitory bacteria compounds from marine Streptomyces. Method: Using 8 test strains, 256 Streptomyces from ocean were screened with their activities against bacteria. Strain M097 was selected to get an optimum condition. Active compounds have been isolated from the crude extraction by fermentation, ethyl acetate extraction, column chromatography etc. Result: The proportion of active marine streptomyces was 22%. 3 compounds produced by marine Streptomyces M097 were identified as feigrisolides A, B and C respectively. Conclusion: Marine Streptomycetes showed promising prospects in discovery of inhibitory bacterial substances.",

keywords = "Active metabolites, M097, Marine Streptomyces, Test strain",

author = "Cui, {Hong Xia} and Song Qin and Khaled Shaaban and Harmut Laatsch",

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language = "English",

volume = "4",

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TY - JOUR

T1 - Screening of marine Streptomyces with antibacterial activity from JiaoZhou bay and studies on metabolites from strain M097

AU - Cui, Hong Xia

AU - Qin, Song

AU - Shaaban, Khaled

AU - Laatsch, Harmut

PY - 2006/7

Y1 - 2006/7

N2 - Aim: To get inhibitory bacteria compounds from marine Streptomyces. Method: Using 8 test strains, 256 Streptomyces from ocean were screened with their activities against bacteria. Strain M097 was selected to get an optimum condition. Active compounds have been isolated from the crude extraction by fermentation, ethyl acetate extraction, column chromatography etc. Result: The proportion of active marine streptomyces was 22%. 3 compounds produced by marine Streptomyces M097 were identified as feigrisolides A, B and C respectively. Conclusion: Marine Streptomycetes showed promising prospects in discovery of inhibitory bacterial substances.

AB - Aim: To get inhibitory bacteria compounds from marine Streptomyces. Method: Using 8 test strains, 256 Streptomyces from ocean were screened with their activities against bacteria. Strain M097 was selected to get an optimum condition. Active compounds have been isolated from the crude extraction by fermentation, ethyl acetate extraction, column chromatography etc. Result: The proportion of active marine streptomyces was 22%. 3 compounds produced by marine Streptomyces M097 were identified as feigrisolides A, B and C respectively. Conclusion: Marine Streptomycetes showed promising prospects in discovery of inhibitory bacterial substances.

KW - Active metabolites

KW - M097

KW - Marine Streptomyces

KW - Test strain

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M3 - Article

AN - SCOPUS:33746663633

SN - 2095-6975

VL - 4

SP - 308

EP - 311

JO - Chinese Journal of Natural Medicines

JF - Chinese Journal of Natural Medicines

IS - 4

ER -

Screening of marine Streptomyces with antibacterial activity from JiaoZhou bay and studies on metabolites from strain M097

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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