Screw-type device diameter and orthodontic loading influence adjacent bone remodeling

Jonathan Christian Francis, Ulas Oz, Larry L. Cunningham, Pinar Emecen Huja, Richard J. Kryscio, Sarandeep S. Huja

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Objective: To evaluate the effect of diameter and orthodontic loading of a screw-type implantable device on bone remodeling. Materials and Methods: Screw-shaped devices of four distinct diameters, 1.6, 2, 3, and 3.75 mm, were placed into edentulous sites in five skeletally mature beagle dogs (n = 14/dog) following premolar extraction. Using a split-mouth design, devices on one side were loaded using calibrated 2N coil springs. Epifluorescent bone labels were administered intravenous prior to sacrifice. Boneimplant sections (∼ 70 μm) were evaluated to quantify bone formation rate (BFR), and other histomorphometric variables were assessed in the implant supporting bone. Results: The mean BFR ranged from 10.93 percent per year to 38.91 percent per year. BFR in the bone adjacent to the device was lower for the loaded 1.6-mm screws when compared with the nonloaded 1.6-mm screws (P < .01) and the loaded 2.0-, 3.0-, and 3.75-mm diameter screws (P < .01). No significant differences in BFR were noted, regardless of loading condition, between the 2.0-, 3.0-, and 3.75-mm diameter screws. Conclusions: We detected a dramatic reduction in bone remodeling. Although orthodontic loading of 2N did not alter bone remodeling associated with screws with a 2.0-mm diameter or larger, it did decrease bone remodeling adjacent to a loaded 1.6-mm screw. The long-term effect of this diminished remodeling should be further investigated.

Original languageEnglish
Pages (from-to)466-472
Number of pages7
JournalAngle Orthodontist
Volume87
Issue number3
DOIs
StatePublished - May 2017

Bibliographical note

Publisher Copyright:
© 2017 by The EH Angle Education and Research Foundation, Inc.

Keywords

  • Beagle dogs
  • Bone remodeling
  • Mini screws
  • Orthodontic force

ASJC Scopus subject areas

  • Orthodontics

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