Secondhand Tobacco Smoke Exposure and Neuromotor Function in Rural Children

Samrat Yeramaneni; Kim N. Dietrich; Kimberly Yolton; Patrick J. Parsons; Kenneth M. Aldous; Erin N. Haynes

doi:10.1016/j.jpeds.2015.03.014

Secondhand Tobacco Smoke Exposure and Neuromotor Function in Rural Children

Samrat Yeramaneni, Kim N. Dietrich, Kimberly Yolton, Patrick J. Parsons, Kenneth M. Aldous, Erin N. Haynes

Epidemiology & Environmental Health

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

Objective To investigate the relationship between secondhand tobacco smoke (SHS) exposure and neuromotor function in children. Study design We studied 404 children aged 7-9 years who were exposed to SHS and other environmental neurotoxicants. Parents reported smoking habits, and serum cotinine levels were measured in children to determine SHS exposure. The Halstead-Reitan Finger Oscillation Test, Purdue Grooved Pegboard Test-Kiddie version, and Bruininks-Oseretsky Test of Motor Proficiency 2-Short Form were used to assess neuromotor function. Multivariable regression models that accounted for potential confounders were used to evaluate the associations. Results Approximately 50% of the children were exposed to SHS based on serum cotinine measures. Exposure to SHS was significantly associated with motor impairment in children, including diminished visuomotor coordination (P =.01), fine motor integration (P =.01), balance (P =.02), and strength (P =.04) after adjusting for exposures to lead and manganese, age, sex, body mass index, measures of parental cognitive abilities, parental education, and quality of home environment. Conclusion SHS is a neurotoxicant that may be associated with impaired childhood neuromotor function.

Original language	English
Pages (from-to)	253-259.e1
Journal	Journal of Pediatrics
Volume	167
Issue number	2
DOIs	https://doi.org/10.1016/j.jpeds.2015.03.014
State	Published - Aug 1 2015

Bibliographical note

Publisher Copyright:
© 2015 Elsevier Inc.

Funding

Supported by the National Institute of Environmental Health Sciences ( 1R01 ES016531-01 and P30-ES006096 ) and the National Institutes of Health/ National Center for Research Resources (Institutional Clinical and Translational Science Award 5UL1RR026314 ). This work was completed in partial fulfillment of the Doctor of Philosophy degree in Epidemiology in the Department of Environmental Health, Division of Epidemiology and Biostatistics, University of Cincinnati College of Medicine for S.Y. The authors declare no conflicts of interest.

Funders	Funder number
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)	R01ES016531, P30-ES006096
National Center for Research Resources	5UL1RR026314

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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10.1016/j.jpeds.2015.03.014

Cite this

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title = "Secondhand Tobacco Smoke Exposure and Neuromotor Function in Rural Children",

abstract = "Objective To investigate the relationship between secondhand tobacco smoke (SHS) exposure and neuromotor function in children. Study design We studied 404 children aged 7-9 years who were exposed to SHS and other environmental neurotoxicants. Parents reported smoking habits, and serum cotinine levels were measured in children to determine SHS exposure. The Halstead-Reitan Finger Oscillation Test, Purdue Grooved Pegboard Test-Kiddie version, and Bruininks-Oseretsky Test of Motor Proficiency 2-Short Form were used to assess neuromotor function. Multivariable regression models that accounted for potential confounders were used to evaluate the associations. Results Approximately 50\% of the children were exposed to SHS based on serum cotinine measures. Exposure to SHS was significantly associated with motor impairment in children, including diminished visuomotor coordination (P =.01), fine motor integration (P =.01), balance (P =.02), and strength (P =.04) after adjusting for exposures to lead and manganese, age, sex, body mass index, measures of parental cognitive abilities, parental education, and quality of home environment. Conclusion SHS is a neurotoxicant that may be associated with impaired childhood neuromotor function.",

author = "Samrat Yeramaneni and Dietrich, \{Kim N.\} and Kimberly Yolton and Parsons, \{Patrick J.\} and Aldous, \{Kenneth M.\} and Haynes, \{Erin N.\}",

note = "Publisher Copyright: {\textcopyright} 2015 Elsevier Inc.",

year = "2015",

month = aug,

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doi = "10.1016/j.jpeds.2015.03.014",

language = "English",

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AU - Yeramaneni, Samrat

AU - Dietrich, Kim N.

AU - Yolton, Kimberly

AU - Parsons, Patrick J.

AU - Aldous, Kenneth M.

AU - Haynes, Erin N.

PY - 2015/8/1

Y1 - 2015/8/1

N2 - Objective To investigate the relationship between secondhand tobacco smoke (SHS) exposure and neuromotor function in children. Study design We studied 404 children aged 7-9 years who were exposed to SHS and other environmental neurotoxicants. Parents reported smoking habits, and serum cotinine levels were measured in children to determine SHS exposure. The Halstead-Reitan Finger Oscillation Test, Purdue Grooved Pegboard Test-Kiddie version, and Bruininks-Oseretsky Test of Motor Proficiency 2-Short Form were used to assess neuromotor function. Multivariable regression models that accounted for potential confounders were used to evaluate the associations. Results Approximately 50% of the children were exposed to SHS based on serum cotinine measures. Exposure to SHS was significantly associated with motor impairment in children, including diminished visuomotor coordination (P =.01), fine motor integration (P =.01), balance (P =.02), and strength (P =.04) after adjusting for exposures to lead and manganese, age, sex, body mass index, measures of parental cognitive abilities, parental education, and quality of home environment. Conclusion SHS is a neurotoxicant that may be associated with impaired childhood neuromotor function.

AB - Objective To investigate the relationship between secondhand tobacco smoke (SHS) exposure and neuromotor function in children. Study design We studied 404 children aged 7-9 years who were exposed to SHS and other environmental neurotoxicants. Parents reported smoking habits, and serum cotinine levels were measured in children to determine SHS exposure. The Halstead-Reitan Finger Oscillation Test, Purdue Grooved Pegboard Test-Kiddie version, and Bruininks-Oseretsky Test of Motor Proficiency 2-Short Form were used to assess neuromotor function. Multivariable regression models that accounted for potential confounders were used to evaluate the associations. Results Approximately 50% of the children were exposed to SHS based on serum cotinine measures. Exposure to SHS was significantly associated with motor impairment in children, including diminished visuomotor coordination (P =.01), fine motor integration (P =.01), balance (P =.02), and strength (P =.04) after adjusting for exposures to lead and manganese, age, sex, body mass index, measures of parental cognitive abilities, parental education, and quality of home environment. Conclusion SHS is a neurotoxicant that may be associated with impaired childhood neuromotor function.

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Secondhand Tobacco Smoke Exposure and Neuromotor Function in Rural Children

Abstract

Bibliographical note

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ASJC Scopus subject areas

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