Sedentary behavior and blood pressure control among osteoarthritis initiative participants

M. W. Sohn, L. M. Manheim, R. W. Chang, P. Greenland, M. C. Hochberg, M. C. Nevitt, P. A. Semanik, D. D. Dunlop

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


OBJECTIVE: To examine the association between sedentary behavior and blood pressure (BP) among Osteoarthritis Initiative (OAI) participants.

DESIGN: We conducted a cross-sectional analysis of the OAI 48-month visit participants whose physical activity was measured using accelerometers. Participants were classified into four quartiles according to the percentage of wear time that was sedentary (<100 activity counts per min). Users of antihypertensive medications or non-steroidal anti-inflammatory drugs (NSAIDs) were excluded. Our main outcomes were systolic and diastolic blood pressures (SBP and DBP) and "elevated BP" defined as BP ≥ 130/85 mm Hg.

RESULTS: For this study cohort (N = 707), mean BP was 121.4 ± 15.6/74.7 ± 9.5 mm Hg and 33% had elevated BP. SBP had a graded association with increased sedentary time (P for trend = 0.02). The most sedentary quartile had 4.26 mm Hg higher SBP (95% confidence interval (CI), 0.69-7.82; P = 0.02) than the least sedentary quartile, adjusting for age, moderate-to-vigorous (MV) physical activity, and other demographic and health factors. The probability of having elevated BP significantly increased in higher sedentary quartiles (P for trend = 0.046). There were no significant findings for DBP.

CONCLUSION: A strong graded association was demonstrated between sedentary behavior and increased SBP and elevated BP, independent of time spent in MV physical activity. Reducing daily sedentary time may lead to improvement in BP and reduction in cardiovascular risk.

Original languageEnglish
Pages (from-to)1234-1240
Number of pages7
JournalOsteoarthritis and Cartilage
Issue number9
StatePublished - Sep 1 2014

Bibliographical note

Funding Information:
This study was funded by the NIH / NIAMS (grants R01AR052912 and P60AR064464 ) and by Falk Medical Trust Research Funds . The sponsors played no role in the design of the study, analysis or interpretation of findings, or drafting the manuscript and did not review or approve the manuscript prior to submission. The authors assume full responsibility for the accuracy and completeness of the ideas presented.

Publisher Copyright:
Published by Elsevier Ltd.


  • Blood pressure
  • Osteoarthritis
  • Physical activity
  • Sedentary lifestyle

ASJC Scopus subject areas

  • Rheumatology
  • Biomedical Engineering
  • Orthopedics and Sports Medicine


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