Serial aEEG recordings in a cohort of extremely preterm infants: Feasibility and safety

A. S. Davis, M. G. Gantz, B. Do, S. Shankaran, S. E.G. Hamrick, K. A. Kennedy, J. E. Tyson, L. F. Chalak, A. R. Laptook, R. F. Goldstein, S. R. Hintz, A. Das, R. D. Higgins, M. B. Ball, E. C. Hale, K. P. Van Meurs

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Objective:Amplitude-integrated electroencephalography (aEEG) monitoring is increasing in the neonatal population, but the safety and feasibility of performing aEEG in extremely preterm infants have not been systematically evaluated.Study Design:Inborn infants 23 0/7 to 28 6/7 weeks gestation or birth weight 401 to 1000 g were eligible. Serial, 6-h aEEG recordings were obtained from first week of life until 36 weeks postmenstrual age. Adverse events were documented, and surveys evaluated the impact of the aEEGs on routine care. Success of performing aEEGs according to protocol and aEEG quality were assessed.Result:A total of 102 infants were enrolled, with 755 recordings performed. 83% of recordings were performed according to schedule, and 96% were without adverse event. Bedside nurses reported no interference with routine care for 89% of recordings. 92% of recordings had acceptable signal quality.Conclusion:Serial aEEG monitoring is safe in preterm infants, with few adverse events and general acceptance by nursing staff.

Original languageEnglish
Pages (from-to)373-378
Number of pages6
JournalJournal of Perinatology
Issue number5
StatePublished - May 30 2015

Bibliographical note

Publisher Copyright:
© 2015 Nature America, Inc.

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology


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