Seroepidemiologic Study of Oropouche Virus, Amazonas State, Brazil, 2015–2016

Julia Forato; Gabriel C. Scachetti; Bárbara B. Salgado; Carolina M.L. Singh; Nadielle C. Pereira; Renato Dos Santos Reis; William M. de Souza; José Luiz Proença-Modena; Pritesh Lalwani

doi:10.3201/eid3204.250917

Seroepidemiologic Study of Oropouche Virus, Amazonas State, Brazil, 2015–2016

Julia Forato
, Gabriel C. Scachetti
, Bárbara B. Salgado
, Carolina M.L. Singh
, Nadielle C. Pereira
, Renato Dos Santos Reis
, William M. de Souza
, José Luiz Proença-Modena
, Pritesh Lalwani

Microbiology, Immunology, and Molecular Genetics

Research output: Contribution to journal › Letter › peer-review

Abstract

We conducted a cross-sectional serosurvey for Oropouche virus (OROV) among residents of Amazonas State, Brazil, during 2015–2016. We detected OROV neutralizing antibodies in 85/814 (10.4%) participants; seroprevalence was higher in Manaus (49/440 [11.1%]) than in Coari (36/374 [9.6%]). Those findings suggest OROV circulation in Amazonas State before 2015.

Original language	English
Pages (from-to)	660-663
Number of pages	4
Journal	Emerging Infectious Diseases
Volume	32
Issue number	4
DOIs	https://doi.org/10.3201/eid3204.250917
State	Published - Apr 2026

Bibliographical note

Publisher Copyright:
© 2026, Centers for Disease Control and Prevention (CDC). All rights reserved.

Funding

P.L. is supported by Fundação de Amparo à Pesquisa do Estado do Amazonas (Posgrad, CT&I Áreas Prioritárias, Iniciativa Amazônia +10, Chamada ERC 2022, and PEX-CT&I/FAPEAM); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Funding 001). J.L.P.M. is supported by São Paulo Research Foundation (no. 2022/10442-0), and National Council for Scientific and Technological Development (CNPq, no. 309971/2023-3). W.M.dS. is supported by Burroughs Wellcome Fund – Climate Change and Human Health Seed Grants (no. 1022448), and Wellcome Trust–Digital Technology Development Award in Climate Sensitive Infectious Disease Modelling (no. 226075/Z/22/Z). J.F. is supported by the São Paulo Research Foundation (grant no. 25/18991-0). G.C.S. is supported by the São Paulo Research Foundation (grant no. 24/12668-0). B.B.S. is supported by Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (grant no. 88887.967871/2024-00).

Funders	Funder number
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Fundação de Amparo à Pesquisa do Estado do Amazonas
Conselho Nacional de Desenvolvimento Científico e Tecnológico	309971/2023-3
Wellcome Trust	226075/Z/22/Z, 88887.967871/2024-00, 24/12668-0, 25/18991-0
Fundação de Amparo à Pesquisa do Estado de São Paulo	2022/10442-0
Chamada ERC	2022
Burroughs Wellcome Fund	1022448

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

ASJC Scopus subject areas

Epidemiology
Microbiology (medical)
Infectious Diseases

Access to Document

10.3201/eid3204.250917

Cite this

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title = "Seroepidemiologic Study of Oropouche Virus, Amazonas State, Brazil, 2015{\textendash}2016",

abstract = "We conducted a cross-sectional serosurvey for Oropouche virus (OROV) among residents of Amazonas State, Brazil, during 2015{\textendash}2016. We detected OROV neutralizing antibodies in 85/814 (10.4\%) participants; seroprevalence was higher in Manaus (49/440 [11.1\%]) than in Coari (36/374 [9.6\%]). Those findings suggest OROV circulation in Amazonas State before 2015.",

author = "Julia Forato and Scachetti, \{Gabriel C.\} and Salgado, \{B{\'a}rbara B.\} and Singh, \{Carolina M.L.\} and Pereira, \{Nadielle C.\} and \{Dos Santos Reis\}, Renato and \{de Souza\}, \{William M.\} and Proen{\c c}a-Modena, \{Jos{\'e} Luiz\} and Pritesh Lalwani",

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doi = "10.3201/eid3204.250917",

language = "English",

volume = "32",

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AU - Forato, Julia

AU - Scachetti, Gabriel C.

AU - Salgado, Bárbara B.

AU - Singh, Carolina M.L.

AU - Pereira, Nadielle C.

AU - Dos Santos Reis, Renato

AU - de Souza, William M.

AU - Proença-Modena, José Luiz

AU - Lalwani, Pritesh

PY - 2026/4

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AB - We conducted a cross-sectional serosurvey for Oropouche virus (OROV) among residents of Amazonas State, Brazil, during 2015–2016. We detected OROV neutralizing antibodies in 85/814 (10.4%) participants; seroprevalence was higher in Manaus (49/440 [11.1%]) than in Coari (36/374 [9.6%]). Those findings suggest OROV circulation in Amazonas State before 2015.

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EP - 663

JO - Emerging Infectious Diseases

JF - Emerging Infectious Diseases

IS - 4

ER -

Seroepidemiologic Study of Oropouche Virus, Amazonas State, Brazil, 2015–2016

Abstract

Bibliographical note

Funding

UN SDGs

ASJC Scopus subject areas

Access to Document

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