Severe calcium pyrophosphate dihydrate deposition disease of the metacarpophalangeal joints

Cody A. Rigsbee, Travis C. Sizemore, Kristine M. Lohr

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


We report a case of calcium pyrophosphate deposition disease (CPPD) with an unusual presentation of severe chondrocalcinosis with atypical large burden deposited in the metacarpophalangeal joints as well as more typical deposition in wrists and knees as demonstrated on plain radiographs. A 77-year-old African-American woman 1-year status post parathyroidectomy for hyperparathyroidism initially presented to the rheumatology clinic to treat suspected rheumatoid arthritis given her pattern of joint involvement but was found to have CPPD. The patient's history is notable for end-stage renal disease which complicates medical management. This case illustrates radiographic findings of CPPD and explores the challenges of treating CPPD in the setting of comorbid conditions.

Original languageEnglish
Article number178
JournalBMJ Case Reports
StatePublished - Sep 28 2018

Bibliographical note

Publisher Copyright:
© © BMJ Publishing Group Limited 2018. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.


  • degenerative joint disease
  • gout
  • rheumatology

ASJC Scopus subject areas

  • General Medicine


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