TY - JOUR
T1 - Single step synthesis, characterization and applications of curcumin functionalized iron oxide magnetic nanoparticles
AU - Bhandari, Rohit
AU - Gupta, Prachi
AU - Dziubla, Thomas
AU - Hilt, J. Zach
N1 - Publisher Copyright:
© 2016 Published by Elsevier B.V.
PY - 2016/10/1
Y1 - 2016/10/1
N2 - Magnetic iron oxide nanoparticles have been well known for their applications in magnetic resonance imaging (MRI), hyperthermia, targeted drug delivery, etc. The surface modification of these magnetic nanoparticles has been explored extensively to achieve functionalized materials with potential application in biomedical, environmental and catalysis field. Herein, we report a novel and versatile single step methodology for developing curcumin functionalized magnetic Fe3O4 nanoparticles without any additional linkers, using a simple coprecipitation technique. The magnetic nanoparticles (MNPs) were characterized using transmission electron microscopy, X-ray diffraction, fourier transform infrared spectroscopy and thermogravimetric analysis. The developed MNPs were employed in a cellular application for protection against an inflammatory agent, a polychlorinated biphenyl (PCB) molecule.
AB - Magnetic iron oxide nanoparticles have been well known for their applications in magnetic resonance imaging (MRI), hyperthermia, targeted drug delivery, etc. The surface modification of these magnetic nanoparticles has been explored extensively to achieve functionalized materials with potential application in biomedical, environmental and catalysis field. Herein, we report a novel and versatile single step methodology for developing curcumin functionalized magnetic Fe3O4 nanoparticles without any additional linkers, using a simple coprecipitation technique. The magnetic nanoparticles (MNPs) were characterized using transmission electron microscopy, X-ray diffraction, fourier transform infrared spectroscopy and thermogravimetric analysis. The developed MNPs were employed in a cellular application for protection against an inflammatory agent, a polychlorinated biphenyl (PCB) molecule.
KW - Anti-inflammatory
KW - Cell viability
KW - Curcumin
KW - Functionalization
KW - Iron oxide
UR - http://www.scopus.com/inward/record.url?scp=84973349018&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84973349018&partnerID=8YFLogxK
U2 - 10.1016/j.msec.2016.04.093
DO - 10.1016/j.msec.2016.04.093
M3 - Article
C2 - 27287099
AN - SCOPUS:84973349018
SN - 0928-4931
VL - 67
SP - 59
EP - 64
JO - Materials Science and Engineering C
JF - Materials Science and Engineering C
ER -