Abstract
Roberts et al. have provided an insightful counterpoint to our review article on the utility of the synergist ablation model. The purpose of this review is to provide some further dialogue regarding the strengths and weaknesses of the synergist ablation model. Specifically, we highlight that the robustness of the model overshadows surgical limitations. We also compare the transcriptomic responses to synergist ablation in mice and resistance exercise in humans to identify common pathways. We conclude that “cell growth is cell growth” and that the mechanisms available to cells to accumulate biomass and increase in size are similar across cell types and independent of the rate of growth.
Original language | English |
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Pages (from-to) | C614-C618 |
Journal | American Journal of Physiology - Cell Physiology |
Volume | 327 |
Issue number | 3 |
DOIs | |
State | Published - Aug 2024 |
Bibliographical note
Publisher Copyright:Copyright © 2024 The Authors Licensed under Creative Commons Attribution CC-BY 4.0.
Keywords
- hypertrophy
- muscle
- resistance training
- synergist ablation
ASJC Scopus subject areas
- Physiology
- Cell Biology