Skeletal Scintigraphy in Radiation-Induced Fibrosis With Lymphedema

Jieqi Wang, Arya M. Iranmanesh, M. Elizabeth Oates

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Despite increasing reliance on CT, MRI, and FDG PET/CT for oncological imaging, whole-body skeletal scintigraphy remains a frontline modality for staging and surveillance of osseous metastatic disease. We present a 54-year-old woman with metastatic breast cancer who received palliative external-beam radiation to the left ilium. Serial follow-up 99mTc-MDP bone scans demonstrated progressive soft-tissue uptake in her left lower extremity, extending from thigh to leg, with associated enlargement and skin thickening, consistent with lymphedema related to radiation-induced fibrosis. Correlative abdominopelvic CT scans confirmed fibrotic changes in the left thigh.

Original languageEnglish
Pages (from-to)231-234
Number of pages4
JournalClinical Nuclear Medicine
Volume42
Issue number3
DOIs
StatePublished - Mar 1 2017

Bibliographical note

Publisher Copyright:
© Wolters Kluwer Health, Inc. All rights reserved.

Keywords

  • bone scan
  • external-beam radiation
  • fibrosis
  • lymphedema
  • radionuclide imaging

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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