Skeletal Scintigraphy in Radiation-Induced Fibrosis With Lymphedema

Jieqi Wang, Arya M. Iranmanesh, M. Elizabeth Oates

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Despite increasing reliance on CT, MRI, and FDG PET/CT for oncological imaging, whole-body skeletal scintigraphy remains a frontline modality for staging and surveillance of osseous metastatic disease. We present a 54-year-old woman with metastatic breast cancer who received palliative external-beam radiation to the left ilium. Serial follow-up Tc-MDP bone scans demonstrated progressive soft-tissue uptake in her left lower extremity, extending from thigh to leg, with associated enlargement and skin thickening, consistent with lymphedema related to radiation-induced fibrosis. Correlative abdominopelvic CT scans confirmed fibrotic changes in the left thigh.

Original languageEnglish
Pages (from-to)231-234
Number of pages4
JournalClinical Nuclear Medicine
Issue number3
StatePublished - Mar 1 2017

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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