Sleep-Disordered Breathing in Möbius Syndrome

Robin L. Gilmore, Robert Baumann, Peggy Falace, Jamshed Kanga

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

Möbius syndrome is a complex neurologic disorder characterized by congenital bilateral facial paralysis associated with lateral gaze paralysis. The syndrome has variable manifestations and several variants, some with somatic stigmata. In 1990, Möbius syndrome is conceptualized as a spectrum of clinical caudal brain-stem signs. Some deficits are manifested by laryngeal paralysis and aspiration. Sleep-disordered breathing syndromes have not been previously reported in association with Möbius syndrome. We report two children with Möbius syndrome and sleep-disordered breathing. Based on known pathologic findings and clinical manifestations, we believe that sleep-disordered breathing may be a common complication of Möbius syndrome and should be sought, since potential outcomes of such complications include serious morbidity.

Original languageEnglish
Pages (from-to)73-77
Number of pages5
JournalJournal of Child Neurology
Volume6
Issue number1
DOIs
StatePublished - Jan 1991

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

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