Abstract
We injected biotinylated dextran amine (BDA) into marginal shell regions of the anteroventral cochlear nucleus (AVCN) of the cat. These injections led to retrograde labeling of cells including small cells (median soma area = 111 μm2, equivalent diameter = 11.9 μm) in the vestibular nerve root (VNR), just ventral to an anterior part of the AVCN. This is an unexpected new finding. The cells were scattered among BDA-labeled fibers and were oriented parallel to the course of the VNR fibers. We suggest that the small neurons of the VNR might serve as second-order vestibular neurons conveying information from vestibular end organs to the cochlear nucleus (CN) and/or act as interneurons between the olivocochlear fibers in the VNR and the CN.
Original language | English |
---|---|
Pages (from-to) | 295-298 |
Number of pages | 4 |
Journal | Brain Research |
Volume | 700 |
Issue number | 1-2 |
DOIs | |
State | Published - Nov 27 1995 |
Bibliographical note
Funding Information:This study was supported in part by grants R01DC00360 and P01DC01366 from NIDCD, NIH. We thank Drs. E. Mugnaini, E.M. Ostapoff, D.L. Oliver, and D.K. Morest for comments, and Dr. D.K. Morest for help in determining cytoarchitectonic subdivisions of the cochlear nucleus.
Keywords
- Auditory brain stem
- Biotinylated dextran amine
- Granule cells
- Olivocochlear fibers
- Retrograde transport
- Small cell cap
ASJC Scopus subject areas
- General Neuroscience
- Molecular Biology
- Clinical Neurology
- Developmental Biology