The phosphoprotein (P) of the nucleorhabdovirus sonchus yellow net virus has been shown to accumulate in ring-shaped structures in virus-infected nuclei. Further examination by live-cell imaging, in combination with structural examination by transmission electron microscopy and immunolocalization demonstrated that P-rings do not form in association with nucleoli. Furthermore, viral cores were shown to condense on the nucleoplasm-contacting surface of the rings. The data presented here offer evidence for the site of nucleocapsid assembly in SYNV-infected nuclei.
|Number of pages||4|
|State||Published - Oct 15 2018|
Bibliographical noteFunding Information:
This research was supported, in part, by grant 0749519 from the U.S. National Science Foundation and KSEF-3490-RDE-019 from the Kentucky Science and Engineering Foundation awarded to M.G.
- Inner nuclear membrane
- Nicotiana benthamiana
ASJC Scopus subject areas
- Cancer Research
- Infectious Diseases