Abstract
This correspondence extends Karl and Pien's ["High-Resolution Biosensor Spectral Peak Shift Estimation,"IEEE Transactions on Signal Processing, vol 53, no. 12, pp. 4631-4639, December 2005] approach to spectral-shift estimation for optical sensors to account for wavelength dependent illumination sources and detectors. Relaxing the assumption of spectrally uniform source power and detector efficiency alters the previously derived Cramér-Rao bound and maximum-likelihood estimator. The new estimator offers significantly reduced error compared to the wavelength invariant estimator and common ad hoc estimators.
Original language | English |
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Pages (from-to) | 5269-5272 |
Number of pages | 4 |
Journal | IEEE Transactions on Signal Processing |
Volume | 56 |
Issue number | 10 II |
DOIs | |
State | Published - 2008 |
Bibliographical note
Funding Information:Manuscript received January 2, 2008; revised June 21, 2008. First published July 25, 2008; current version published September 17, 2008. The associate editor coordinating the review of this manuscript and approving it for publication was Dr. Tryphon T. Georgiou. This material is based upon work supported by the National Science Foundation under Grant 0716486.
Keywords
- Cramér-Rao lower bound
- Optical sensors
- Spectral peakshift estimation
ASJC Scopus subject areas
- Signal Processing
- Electrical and Electronic Engineering