@article{a0754510f9cb418980a6695765b6422d,
title = "Spectrophotometric Prediction of the Dissolution Rate of Carbamazepine Tablets",
abstract = "A near-infrared (IR) spectrophotometer, integrating optics, and parallel-vector supercomputer are employed to develop a mathematical model that predicts the dissolution rate of individual intact tablets from near-IR spectra (r2 = 0.985). Each tablet can be analyzed nondestructively by the spectrophotometer in less than 1 min. The model permits hundreds of near-IR wavelengths to be used in the determination of dissolution rate, leading to increased accuracy.",
keywords = "degradation product, dissolution rate, intact tablets, moisture effects, near-infrared (IR)",
author = "Zannikos, \{Peter N.\} and Li, \{Wen I.\} and Drennen, \{James K.\} and Lodder, \{Robert A.\}",
year = "1991",
month = aug,
doi = "10.1023/A:1015840604423",
language = "English",
volume = "8",
pages = "974--978",
number = "8",
}