Abstract
Spinal cord compression as a consequence of mass lesions due to extramedullary hematopoiesis is a well-described but rare syndrome occurring in thalassemia and some other hematologic conditions. After low-dose radiotherapy alone, a rapid and durable response occurred in a patient with thalassemia. No side effects were encountered and the patient has been stable neurologically for over 7 years since treatment. The results of the current case, and those previously reported in which radiotherapy alone was given, suggest that low-dose radiotherapy should be considered as a primary treatment modality for the management of this syndrome, at least in patients with thalassemia.
| Original language | English |
|---|---|
| Pages (from-to) | 389-392 |
| Number of pages | 4 |
| Journal | Surgical Neurology |
| Volume | 29 |
| Issue number | 5 |
| DOIs | |
| State | Published - May 1988 |
Bibliographical note
Funding Information:The authorsw ish to thank Mrs. Jane Moye for manuscripptr epara-tion. This study was supportedin part by grant CA-12197 from the National Instituteso f Health.
Keywords
- Cord compression
- Extramedullary hematopoiesis
- Radiation therapy
- Thalassemia
ASJC Scopus subject areas
- Surgery
- Clinical Neurology