Spontaneous coronary thrombosis following thrombolytic therapy for acute cardiovascular accident and stroke: A case study

Eric L. Wallace; Susan S. Smyth

doi:10.1007/s11239-012-0754-2

Spontaneous coronary thrombosis following thrombolytic therapy for acute cardiovascular accident and stroke: A case study

Eric L. Wallace, Susan S. Smyth

Internal Medicine

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Cardiac complications following stroke or acute cerebrovascular accidents (CVA) are common; however, many of these complications are asymptomatic and do not cause adverse cardiac effects. Symptomatic events (such as acute myocardial infarction after CVA) rarely occur and are often the result of an underlying cardiac embolic source, such as a left ventricular thrombus. We report a case of spontaneous coronary thrombosis following thrombolytic therapy for acute CVA, and discuss the implication that an underlying systemic pro-thrombotic state may predispose individuals to thrombosis in disparate vascular beds.

Original language	English
Pages (from-to)	548-551
Number of pages	4
Journal	Journal of Thrombosis and Thrombolysis
Volume	34
Issue number	4
DOIs	https://doi.org/10.1007/s11239-012-0754-2
State	Published - Nov 2012

Bibliographical note

Funding Information:
Acknowledgments The authors wish to thank Susan Quick for outstanding editorial support. This work was supported by the National Center for Research Resources and the National Center for Advancing Translational Sciences, National Institutes of Health, through Grant 1UL1RR033173. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. This work was also supported by resources and/or the use of facilities at the Lexington VA Medical Center.

Funding

Acknowledgments The authors wish to thank Susan Quick for outstanding editorial support. This work was supported by the National Center for Research Resources and the National Center for Advancing Translational Sciences, National Institutes of Health, through Grant 1UL1RR033173. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. This work was also supported by resources and/or the use of facilities at the Lexington VA Medical Center.

Funders	Funder number
National Institutes of Health (NIH)
National Center for Research Resources	UL1RR033173
National Center for Advancing Translational Sciences (NCATS)

Keywords

Acute cerebrovascular accidents
Stroke
Thrombolytic therapy
Thrombosis

ASJC Scopus subject areas

Hematology
Cardiology and Cardiovascular Medicine

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10.1007/s11239-012-0754-2

Cite this

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title = "Spontaneous coronary thrombosis following thrombolytic therapy for acute cardiovascular accident and stroke: A case study",

abstract = "Cardiac complications following stroke or acute cerebrovascular accidents (CVA) are common; however, many of these complications are asymptomatic and do not cause adverse cardiac effects. Symptomatic events (such as acute myocardial infarction after CVA) rarely occur and are often the result of an underlying cardiac embolic source, such as a left ventricular thrombus. We report a case of spontaneous coronary thrombosis following thrombolytic therapy for acute CVA, and discuss the implication that an underlying systemic pro-thrombotic state may predispose individuals to thrombosis in disparate vascular beds.",

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AU - Smyth, Susan S.

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PY - 2012/11

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N2 - Cardiac complications following stroke or acute cerebrovascular accidents (CVA) are common; however, many of these complications are asymptomatic and do not cause adverse cardiac effects. Symptomatic events (such as acute myocardial infarction after CVA) rarely occur and are often the result of an underlying cardiac embolic source, such as a left ventricular thrombus. We report a case of spontaneous coronary thrombosis following thrombolytic therapy for acute CVA, and discuss the implication that an underlying systemic pro-thrombotic state may predispose individuals to thrombosis in disparate vascular beds.

AB - Cardiac complications following stroke or acute cerebrovascular accidents (CVA) are common; however, many of these complications are asymptomatic and do not cause adverse cardiac effects. Symptomatic events (such as acute myocardial infarction after CVA) rarely occur and are often the result of an underlying cardiac embolic source, such as a left ventricular thrombus. We report a case of spontaneous coronary thrombosis following thrombolytic therapy for acute CVA, and discuss the implication that an underlying systemic pro-thrombotic state may predispose individuals to thrombosis in disparate vascular beds.

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KW - Thrombolytic therapy

KW - Thrombosis

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Spontaneous coronary thrombosis following thrombolytic therapy for acute cardiovascular accident and stroke: A case study

Abstract

Bibliographical note

Funding

Keywords

ASJC Scopus subject areas

Access to Document

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