Spontaneous pyohaemothorax in a teenager with von Willebrand disease: a case report and review of literature

Vaishnavi Divya Nagarajan; Asha Shenoi; Lucy Burgess; Vlad C. Radulescu

doi:10.1136/bcr-2021-241613

Spontaneous pyohaemothorax in a teenager with von Willebrand disease: a case report and review of literature

Vaishnavi Divya Nagarajan, Asha Shenoi, Lucy Burgess, Vlad C. Radulescu

Pediatrics

Research output: Contribution to journal › Article › peer-review

Abstract

An 18-year-old man with a history of type 3 von Willebrand disease (VWD) presented with a spontaneous pyohaemothorax. Type 3 VWD may present with both mucocutaneous and deep-seated bleeds, such as visceral haemorrhages, intracranial bleeds and haemarthrosis. There have been very few cases described in children of spontaneous pyohaemothorax. Management of this patient was challenging due to risks of bleeding following surgical drainage, requiring constant replacement with von Willebrand factor concentrate, while monitoring factor VIII levels to balance the risks of thrombosis.

Original language	English
Journal	BMJ Case Reports
Volume	14
Issue number	8
DOIs	https://doi.org/10.1136/bcr-2021-241613
State	Published - Aug 17 2021

Bibliographical note

Publisher Copyright:
© BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.

Keywords

haematology (incl blood transfusion)
paediatrics (drugs and medicines)

ASJC Scopus subject areas

General Medicine

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10.1136/bcr-2021-241613

Cite this

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abstract = "An 18-year-old man with a history of type 3 von Willebrand disease (VWD) presented with a spontaneous pyohaemothorax. Type 3 VWD may present with both mucocutaneous and deep-seated bleeds, such as visceral haemorrhages, intracranial bleeds and haemarthrosis. There have been very few cases described in children of spontaneous pyohaemothorax. Management of this patient was challenging due to risks of bleeding following surgical drainage, requiring constant replacement with von Willebrand factor concentrate, while monitoring factor VIII levels to balance the risks of thrombosis.",

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AU - Burgess, Lucy

AU - Radulescu, Vlad C.

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AB - An 18-year-old man with a history of type 3 von Willebrand disease (VWD) presented with a spontaneous pyohaemothorax. Type 3 VWD may present with both mucocutaneous and deep-seated bleeds, such as visceral haemorrhages, intracranial bleeds and haemarthrosis. There have been very few cases described in children of spontaneous pyohaemothorax. Management of this patient was challenging due to risks of bleeding following surgical drainage, requiring constant replacement with von Willebrand factor concentrate, while monitoring factor VIII levels to balance the risks of thrombosis.

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Spontaneous pyohaemothorax in a teenager with von Willebrand disease: a case report and review of literature

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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