TY - JOUR
T1 - Stability of erp loci during Borrelia burgdorferi infection
T2 - Recombination is not required for chronic infection of immunocompetent mice
AU - El Hage, Nazira
AU - Lieto, Louis D.
AU - Stevenson, Brian
PY - 1999/6
Y1 - 1999/6
N2 - Borrelia burgdorferi can persistently infect mammals despite their production of antibodies directed against bacterial proteins, including the Erp lipoproteins. We sequenced erp loci of bacteria reisolated from laboratory mice after 1 year of infection and found them to be identical to those of the inoculant bacteria. We conclude that recombination of erp genes is not essential for chronic mammalian infection.
AB - Borrelia burgdorferi can persistently infect mammals despite their production of antibodies directed against bacterial proteins, including the Erp lipoproteins. We sequenced erp loci of bacteria reisolated from laboratory mice after 1 year of infection and found them to be identical to those of the inoculant bacteria. We conclude that recombination of erp genes is not essential for chronic mammalian infection.
UR - http://www.scopus.com/inward/record.url?scp=0033022539&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033022539&partnerID=8YFLogxK
U2 - 10.1128/iai.67.6.3146-3150.1999
DO - 10.1128/iai.67.6.3146-3150.1999
M3 - Article
C2 - 10338534
AN - SCOPUS:0033022539
SN - 0019-9567
VL - 67
SP - 3146
EP - 3150
JO - Infection and Immunity
JF - Infection and Immunity
IS - 6
ER -
