Little is known regarding the appropriate timing and sequencing of a carbapenem and polymyxin in combination against carbapenem-resistant Enterobacteriaceae. Meropenem and polymyxin B were administered simultaneously or 1 agent 2 h prior to the other, in vitro. The carbapenem should be administered prior to the polymyxin when used in combination.
|Number of pages||4|
|Journal||Diagnostic Microbiology and Infectious Disease|
|State||Published - Mar 2019|
Bibliographical notePublisher Copyright:
© 2018 Elsevier Inc.
- Carbapenem-resistant Enterobacteriaceae
- Polymyxin B
- Staggered administration
ASJC Scopus subject areas
- Microbiology (medical)
- Infectious Diseases