TY - JOUR
T1 - Staggering the administration of polymyxin B and meropenem in time-kill against carbapenem-resistant Enterobacteriaceae exhibiting a wide range of meropenem MICs
AU - Kulengowski, Brandon
AU - Clark, Justin A.
AU - Burgess, David S.
N1 - Publisher Copyright:
© 2018 Elsevier Inc.
PY - 2019/3
Y1 - 2019/3
N2 - Little is known regarding the appropriate timing and sequencing of a carbapenem and polymyxin in combination against carbapenem-resistant Enterobacteriaceae. Meropenem and polymyxin B were administered simultaneously or 1 agent 2 h prior to the other, in vitro. The carbapenem should be administered prior to the polymyxin when used in combination.
AB - Little is known regarding the appropriate timing and sequencing of a carbapenem and polymyxin in combination against carbapenem-resistant Enterobacteriaceae. Meropenem and polymyxin B were administered simultaneously or 1 agent 2 h prior to the other, in vitro. The carbapenem should be administered prior to the polymyxin when used in combination.
KW - Carbapenem-resistant Enterobacteriaceae
KW - Meropenem
KW - Polymyxin B
KW - Staggered administration
KW - Time-kill
UR - http://www.scopus.com/inward/record.url?scp=85055049852&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85055049852&partnerID=8YFLogxK
U2 - 10.1016/j.diagmicrobio.2018.09.014
DO - 10.1016/j.diagmicrobio.2018.09.014
M3 - Article
C2 - 30344066
AN - SCOPUS:85055049852
SN - 0732-8893
VL - 93
SP - 261
EP - 264
JO - Diagnostic Microbiology and Infectious Disease
JF - Diagnostic Microbiology and Infectious Disease
IS - 3
ER -
