Standard operating procedures for biospecimen collection, processing, and storage: From the consortium for the study of chronic pancreatitis, diabetes, and pancreatic cancer

William E. Fisher; Zobeida Cruz-Monserrate; Amy L. McElhany; Gregory B. Lesinski; Phil A. Hart; Ria Ghosh; George Van Buren; Douglas S. Fishman; Jo Ann S. Rinaudo; Jose Serrano; Sudhir Srivastava; Thomas MacE; Mark Topazian; Ziding Feng; Dhiraj Yadav; Stephen J. Pandol; Steven J. Hughes; Robert Y. Liu; Emily Lu; Robert Orr; David C. Whitcomb; Amer S. Abouhamze; Hanno Steen; Zachary M. Sellers; David M. Troendle; Aliye Uc; Mark E. Lowe; Darwin L. Conwell

doi:10.1097/MPA.0000000000001171

Standard operating procedures for biospecimen collection, processing, and storage: From the consortium for the study of chronic pancreatitis, diabetes, and pancreatic cancer

William E. Fisher, Zobeida Cruz-Monserrate, Amy L. McElhany, Gregory B. Lesinski, Phil A. Hart, Ria Ghosh, George Van Buren, Douglas S. Fishman, Jo Ann S. Rinaudo, Jose Serrano, Sudhir Srivastava, Thomas MacE, Mark Topazian, Ziding Feng, Dhiraj Yadav, Stephen J. Pandol, Steven J. Hughes, Robert Y. Liu, Emily Lu, Robert OrrDavid C. Whitcomb, Amer S. Abouhamze, Hanno Steen, Zachary M. Sellers, David M. Troendle, Aliye Uc, Mark E. Lowe, Darwin L. Conwell

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

High-quality and well-annotated biorepositories are needed to better understand the pathophysiology and biologic mechanisms of chronic pancreatitis (CP) and its consequences. We report a methodology for the development of a robust standard operating procedure (SOP) for a biorepository based on the experience of the clinical centers within the consortium to study Chronic Pancreatitis, Diabetes and Pancreas Cancer Clinical Centers (CPDPC), supported by the National Cancer Institute and the National Institute for Diabetes and Digestive and Kidney Diseases as a unique multidisciplinary model to study CP, diabetes, and pancreatic cancer in both children and adults. Standard operating procedures from the CPDPC centers were evaluated and consolidated. The literature was reviewed for standard biorepository operating procedures that facilitated downstream molecular analysis. The existing literature on biobanking practices was harmonized with the SOPs from the clinical centers to produce a biorepository for pancreatic research. This article reports the methods and basic principles behind the creation of SOPs to develop a biorepository for the CPDPC. These will serve as a guide for investigators developing biorepositories in pancreas research. Rigorous and meticulous adherence to standardized biospecimen collection will facilitate investigations to better understand the pathophysiology and biologic mechanisms of CP, diabetes, and pancreatic cancer.

Original language	English
Pages (from-to)	1213-1221
Number of pages	9
Journal	Pancreas
Volume	47
Issue number	10
DOIs	https://doi.org/10.1097/MPA.0000000000001171
State	Published - Nov 1 2018

Bibliographical note

Publisher Copyright:
© 2018 Wolters Kluwer Health, Inc. All rights reserved.

Funding

Research reported in this publication was supported by the National Cancer Institute and National Institute of Diabetes and Digestive and Kidney Diseases under award numbers U01DK108326 (Baylor College of Medicine), U01DK108327 (Ohio State University), U01DK108328 (University of Texas MD Anderson Cancer Center), U01DK108288 (Mayo Clinic), U01DK108306 (University of Pittsburgh), U01DK108314 (Cedars-Sinai Medical Center), U01DK108320 (University Of Florida), U01DK108323 (Indiana University), U01DK108300 (Stanford University), and U01 DK108334 (University of Iowa). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. W ell-annotated and characterized human biospecimens are needed to identify potentially diagnostic, prognostic, and predictive biomarkers.1 Through the acquisition of a cohort of well-characterized patients and associated biospecimens (blood, urine, saliva, stool, pancreatic and duodenal juice, stools, and when feasible pancreatic tissue), the proposed clinical research network will provide the resources and collaborative opportunities necessary for achieving many of the research objectives identified by the Chronic Pancreatitis, Diabetes and Pancreas Cancer Clinical Centers (CPDPC). The CPDPC is supported by the National Cancer Institute (NCI) and the National Institute for Diabetes and Digestive and Kidney Diseases (NIDDK) as a unique multidisciplinary model to study chronic pancreatitis, diabetes, and pancreatic cancer in both children and adults. Differences in

Funders	Funder number
National Childhood Cancer Registry – National Cancer Institute
National Institute of Diabetes and Digestive and Kidney Diseases	U01DK108306, U01DK108328, U01DK108327, U01DK108323, U01DK108326, U01DK108314, U01DK108320, U01DK108300, U01DK108288
National Institute of Diabetes and Digestive and Kidney Diseases
Mayo Clinic Rochester
Stanford University	U01 DK108334
Stanford University
University of Southern Indiana
Ohio Water Resources Center, Ohio State University
University of Texas Anderson Cancer Center
Baylor College of Medicine
University of Pittsburgh Medical Center, Children's Hospital of Pittsburgh
Iowa Environmental Mesonet at Iowa State University
Cedars-Sinai Medical Center

Keywords

biorepository
biospecimens
pancreas
standard operating procedures

ASJC Scopus subject areas

Internal Medicine
Endocrinology, Diabetes and Metabolism
Hepatology
Endocrinology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1097/MPA.0000000000001171

Cite this

Fisher, W. E., Cruz-Monserrate, Z., McElhany, A. L., Lesinski, G. B., Hart, P. A., Ghosh, R., Van Buren, G., Fishman, D. S., Rinaudo, J. A. S., Serrano, J., Srivastava, S., MacE, T., Topazian, M., Feng, Z., Yadav, D., Pandol, S. J., Hughes, S. J., Liu, R. Y., Lu, E., ... Conwell, D. L. (2018). Standard operating procedures for biospecimen collection, processing, and storage: From the consortium for the study of chronic pancreatitis, diabetes, and pancreatic cancer. Pancreas, 47(10), 1213-1221. https://doi.org/10.1097/MPA.0000000000001171

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abstract = "High-quality and well-annotated biorepositories are needed to better understand the pathophysiology and biologic mechanisms of chronic pancreatitis (CP) and its consequences. We report a methodology for the development of a robust standard operating procedure (SOP) for a biorepository based on the experience of the clinical centers within the consortium to study Chronic Pancreatitis, Diabetes and Pancreas Cancer Clinical Centers (CPDPC), supported by the National Cancer Institute and the National Institute for Diabetes and Digestive and Kidney Diseases as a unique multidisciplinary model to study CP, diabetes, and pancreatic cancer in both children and adults. Standard operating procedures from the CPDPC centers were evaluated and consolidated. The literature was reviewed for standard biorepository operating procedures that facilitated downstream molecular analysis. The existing literature on biobanking practices was harmonized with the SOPs from the clinical centers to produce a biorepository for pancreatic research. This article reports the methods and basic principles behind the creation of SOPs to develop a biorepository for the CPDPC. These will serve as a guide for investigators developing biorepositories in pancreas research. Rigorous and meticulous adherence to standardized biospecimen collection will facilitate investigations to better understand the pathophysiology and biologic mechanisms of CP, diabetes, and pancreatic cancer.",

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author = "Fisher, {William E.} and Zobeida Cruz-Monserrate and McElhany, {Amy L.} and Lesinski, {Gregory B.} and Hart, {Phil A.} and Ria Ghosh and {Van Buren}, George and Fishman, {Douglas S.} and Rinaudo, {Jo Ann S.} and Jose Serrano and Sudhir Srivastava and Thomas MacE and Mark Topazian and Ziding Feng and Dhiraj Yadav and Pandol, {Stephen J.} and Hughes, {Steven J.} and Liu, {Robert Y.} and Emily Lu and Robert Orr and Whitcomb, {David C.} and Abouhamze, {Amer S.} and Hanno Steen and Sellers, {Zachary M.} and Troendle, {David M.} and Aliye Uc and Lowe, {Mark E.} and Conwell, {Darwin L.}",

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Fisher, WE, Cruz-Monserrate, Z, McElhany, AL, Lesinski, GB, Hart, PA, Ghosh, R, Van Buren, G, Fishman, DS, Rinaudo, JAS, Serrano, J, Srivastava, S, MacE, T, Topazian, M, Feng, Z, Yadav, D, Pandol, SJ, Hughes, SJ, Liu, RY, Lu, E, Orr, R, Whitcomb, DC, Abouhamze, AS, Steen, H, Sellers, ZM, Troendle, DM, Uc, A, Lowe, ME & Conwell, DL 2018, 'Standard operating procedures for biospecimen collection, processing, and storage: From the consortium for the study of chronic pancreatitis, diabetes, and pancreatic cancer', Pancreas, vol. 47, no. 10, pp. 1213-1221. https://doi.org/10.1097/MPA.0000000000001171

Standard operating procedures for biospecimen collection, processing, and storage: From the consortium for the study of chronic pancreatitis, diabetes, and pancreatic cancer. / Fisher, William E.; Cruz-Monserrate, Zobeida; McElhany, Amy L. et al.
In: Pancreas, Vol. 47, No. 10, 01.11.2018, p. 1213-1221.

Research output: Contribution to journal › Article › peer-review

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AU - Fisher, William E.

AU - Cruz-Monserrate, Zobeida

AU - McElhany, Amy L.

AU - Lesinski, Gregory B.

AU - Hart, Phil A.

AU - Ghosh, Ria

AU - Van Buren, George

AU - Fishman, Douglas S.

AU - Rinaudo, Jo Ann S.

AU - Serrano, Jose

AU - Srivastava, Sudhir

AU - MacE, Thomas

AU - Topazian, Mark

AU - Feng, Ziding

AU - Yadav, Dhiraj

AU - Pandol, Stephen J.

AU - Hughes, Steven J.

AU - Liu, Robert Y.

AU - Lu, Emily

AU - Orr, Robert

AU - Whitcomb, David C.

AU - Abouhamze, Amer S.

AU - Steen, Hanno

AU - Sellers, Zachary M.

AU - Troendle, David M.

AU - Uc, Aliye

AU - Lowe, Mark E.

AU - Conwell, Darwin L.

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Standard operating procedures for biospecimen collection, processing, and storage: From the consortium for the study of chronic pancreatitis, diabetes, and pancreatic cancer

Abstract

Bibliographical note

Funding

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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Cite this