Standard Operating Procedures for Biospecimen Collection, Processing, and Storage: From the Type 1 Diabetes in Acute Pancreatitis Consortium

Clive Wasserfall, Anne Marie Dyer, Cate Speake, Dana K. Andersen, Kendall Thomas Baab, Melena D. Bellin, James R. Broach, Martha Campbell-Thompson, Vernon M. Chinchilli, Peter J. Lee, Walter G. Park, Richard E. Pratley, Jami L. Saloman, Emily K. Sims, Gong Tang, Dhiraj Yadav, Cemal Yazici, Darwin L. Conwell

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Differences in methods for biospecimen collection, processing, and storage can yield considerable variability and error. Therefore, best practices for standard operating procedures are critical for successful discovery, development, and validation of disease biomarkers. Here, we describe standard operating procedures developed for biospecimen collection during the DREAM (Diabetes RElated to Acute pancreatitis and its Mechanisms) Study within the Type 1 Diabetes in Acute Pancreatitis Consortium. Notably, these protocols were developed using an integrative process based on prior consortium experience and with input from working groups with expertise in immunology, pancreatitis, and diabetes. Publication and adoption consistent biospecimen protocols will inform future studies and allow for better comparisons across different metabolic research efforts.

Original languageEnglish
Pages (from-to)593-597
Number of pages5
JournalPancreas
Volume51
Issue number6
DOIs
StatePublished - Jul 1 2022

Bibliographical note

Publisher Copyright:
© Wolters Kluwer Health, Inc. All rights reserved.

Keywords

  • AP - acute pancreatitis
  • CPDPC - Chronic Pancreatitis Diabetes Pancreas Cancer Consortium
  • DCC - data coordinating center
  • DKCR - NIDDK Central Repository
  • DREAM - Diabetes RElated to Acute pancreatitis and its Mechanisms
  • LN - liquid nitrogen
  • NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
  • PBMC - peripheral blood mononuclear cells
  • SOP - standard operating procedures
  • ST - sample tracking module
  • T1DAPC - Type 1 Diabetes in Acute Pancreatitis Consortium
  • biorepository
  • biosamples
  • immunology
  • laboratory protocol
  • pancreas
  • type 1 diabetes

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Hepatology
  • Endocrinology

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