Stem cells

Hui Peng; Nicholas Whitney; Kang Tang; Myron Toews; Jialin Zheng

doi:10.1007/978-0-387-72573-4_13

Stem cells

Hui Peng, Nicholas Whitney, Kang Tang, Myron Toews, Jialin Zheng

Pharmaceutical Sciences

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

It is now accepted that neurogenesis continues throughout life, contrary to the previously held dogma that no new neurons are produced in the adult human brain. Neurogenesis during development and throughout adult life is a result of the proliferation, migration, and differentiation of neural stem cells (NSC). NSC are cells that can differentiate into all the cells of the central nervous system (CNS) and self-renew while retaining their multipotential capabilities. Numerous factors contribute to the survival, proliferation, migration, and differentiation of NSC. These factors include, but are not limited to, chemokines, growth factors, and neurotransmitters.

Original language	English
Title of host publication	Neuroimmune Pharmacology
Pages	151-170
Number of pages	20
DOIs	https://doi.org/10.1007/978-0-387-72573-4_13
State	Published - 2008

Keywords

Chemokines
Differentiation
Growth factors
Microglia
Neurogenesis
Neurotransmitters
Proliferation
Self-renewal
Stem cell

ASJC Scopus subject areas

General Pharmacology, Toxicology and Pharmaceutics
General Neuroscience

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10.1007/978-0-387-72573-4_13

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AU - Peng, Hui

AU - Whitney, Nicholas

AU - Tang, Kang

AU - Toews, Myron

AU - Zheng, Jialin

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N2 - It is now accepted that neurogenesis continues throughout life, contrary to the previously held dogma that no new neurons are produced in the adult human brain. Neurogenesis during development and throughout adult life is a result of the proliferation, migration, and differentiation of neural stem cells (NSC). NSC are cells that can differentiate into all the cells of the central nervous system (CNS) and self-renew while retaining their multipotential capabilities. Numerous factors contribute to the survival, proliferation, migration, and differentiation of NSC. These factors include, but are not limited to, chemokines, growth factors, and neurotransmitters.

AB - It is now accepted that neurogenesis continues throughout life, contrary to the previously held dogma that no new neurons are produced in the adult human brain. Neurogenesis during development and throughout adult life is a result of the proliferation, migration, and differentiation of neural stem cells (NSC). NSC are cells that can differentiate into all the cells of the central nervous system (CNS) and self-renew while retaining their multipotential capabilities. Numerous factors contribute to the survival, proliferation, migration, and differentiation of NSC. These factors include, but are not limited to, chemokines, growth factors, and neurotransmitters.

KW - Chemokines

KW - Differentiation

KW - Growth factors

KW - Microglia

KW - Neurogenesis

KW - Neurotransmitters

KW - Proliferation

KW - Self-renewal

KW - Stem cell

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EP - 170

BT - Neuroimmune Pharmacology

ER -

Stem cells

Abstract

Keywords

ASJC Scopus subject areas

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