Stigma, biomarkers, and algorithmic bias: Recommendations for precision behavioral health with artificial intelligence

Colin G. Walsh, Beenish Chaudhry, Prerna Dua, Kenneth W. Goodman, Bonnie Kaplan, Ramakanth Kavuluru, Anthony Solomonides, Vignesh Subbian

Research output: Contribution to journalReview articlepeer-review

57 Scopus citations

Abstract

Effective implementation of artificial intelligence in behavioral healthcare delivery depends on overcoming challenges that are pronounced in this domain. Self and social stigma contribute to under-reported symptoms, and under-coding worsens ascertainment. Health disparities contribute to algorithmic bias. Lack of reliable biological and clinical markers hinders model development, and model explainability challenges impede trust among users. In this perspective, we describe these challenges and discuss design and implementation recommendations to overcome them in intelligent systems for behavioral and mental health.

Original languageEnglish
Pages (from-to)9-15
Number of pages7
JournalJAMIA Open
Volume3
Issue number1
DOIs
StatePublished - 2021

Bibliographical note

Publisher Copyright:
© The Author(s) 2020.

Funding

Authors’ effort were partially supported by the following grants: under grant # W81XWH-10-2-0181 and R01 MH116269-01 (CGW), the National Institute of General Medical Sciences of the National Institutes of Health under grant #P20 GM103424-17 (PD); U.S. National Center for Advancing Translational Sciences via grant #UL1TR001998 (RK); National Science Foundation under grant #1838745 (VS).

FundersFunder number
National Science Foundation (NSF)1838745
National Institutes of Health (NIH)20 GM103424-17
National Institute of Mental HealthR01MH116269
National Institute of General Medical Sciences
National Center for Advancing Translational Sciences (NCATS)1TR001998

    Keywords

    • Algorithms
    • Artificial intelligence
    • Behavioral health
    • Ethics
    • Health disparities
    • Mental health
    • Precision medicine
    • Predictive modeling

    ASJC Scopus subject areas

    • Health Informatics

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