Abstract
Through structural modification of 2-anilinonicotinic acid by isomerization, a new synthon, acid-aminopyridine, is created, and the two original synthons, i.e., the acid-acid homosynthon and acid-pyridine heterosynthon are no longer observed in the newly designed 6-anilinonicotinic acids. The new synthon has a hydrogen-bond strength rivaling that of the acid-acid homosynthon and the acid-pyridine heterosynthon, as suggested by theoretical calculations, which explains its formation.
Original language | English |
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Pages (from-to) | 4849-4859 |
Number of pages | 11 |
Journal | Crystal Growth and Design |
Volume | 18 |
Issue number | 9 |
DOIs | |
State | Published - Sep 5 2018 |
Bibliographical note
Funding Information:S.P. and S.L. thank Natural Science Foundation of Hubei Province (2014CFB787) and the President’s Fund of Wuhan Institute of Technology (CX2016075) for financial support.
ASJC Scopus subject areas
- Chemistry (all)
- Materials Science (all)
- Condensed Matter Physics