Structure, function and regulation of plant proteasomes

Jasmina Kurepa; Jan A. Smalle

doi:10.1016/j.biochi.2007.07.019

Structure, function and regulation of plant proteasomes

Jasmina Kurepa, Jan A. Smalle

Plant and Soil Sciences

Research output: Contribution to journal › Article › peer-review

136 Scopus citations

Abstract

Proteasomes are large multisubunit, multicatalytic proteases responsible for most of the cytosolic and nuclear protein degradation, and their structure and functions are conserved in eukaryotes. Proteasomes were originally identified as the proteolytic module of the ubiquitin-dependent proteolysis pathway. Today we know that proteasomes also mediate ubiquitin-independent proteolysis, that they have RNAse activity, and play a non-proteolytic role in transcriptional regulation. Here we present an overview of the current knowledge of proteasome function and regulation in plants and highlight the role of proteasome-dependent protein degradation in the control of plant development and responses to the environment.

Original language	English
Pages (from-to)	324-335
Number of pages	12
Journal	Biochimie
Volume	90
Issue number	2
DOIs	https://doi.org/10.1016/j.biochi.2007.07.019
State	Published - Feb 2008

Bibliographical note

Funding Information:
We thank D. Zaitlin for critical reading of the manuscript. Research in the laboratory of J.S. is supported by the National Research Initiative of the USDA Cooperative State Research, Education and Extension Service, grant number 2005-35304-16043, and the Kentucky Science and Engineering Foundation, grant number 148-502-06-189.

Keywords

Plant development
Plant responses
Proteasome
Ubiquitin

ASJC Scopus subject areas

Biochemistry

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10.1016/j.biochi.2007.07.019

Cite this

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AU - Smalle, Jan A.

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Structure, function and regulation of plant proteasomes

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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