Sudden Bilateral Hearing Loss, Tinnitus, and Vertigo as Presenting Symptoms of Chronic Myeloid Leukemia

Nathan D. Cass; Samuel P. Gubbels; Cory D.F. Portnuff

doi:10.1177/0003489418787831

Sudden Bilateral Hearing Loss, Tinnitus, and Vertigo as Presenting Symptoms of Chronic Myeloid Leukemia

Nathan D. Cass, Samuel P. Gubbels, Cory D.F. Portnuff

Otolaryngology

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Objectives: The objective was to describe a unique case of sudden bilateral hearing loss, tinnitus, and vertigo presenting as the first symptoms of chronic myeloid leukemia (CML). Methods: A patient case is discussed along with a review of associated literature. Results: A patient presented with sudden onset hearing loss, tinnitus, and vertigo, and was diagnosed with CML with an initial white blood cell (WBC) count of 555 000 per microliter. The proposed etiology of otologic symptoms is hyperleukocytosis. Serial audiograms showed minimal improvement in hearing despite reduction of WBC. Conclusion: In cases of bilateral, sudden onset sensorineural hearing loss, evaluation for systemic causes of otologic symptoms, including CML, should be considered.

Original language	English
Pages (from-to)	731-734
Number of pages	4
Journal	Annals of Otology, Rhinology and Laryngology
Volume	127
Issue number	10
DOIs	https://doi.org/10.1177/0003489418787831
State	Published - Oct 1 2018

Bibliographical note

Publisher Copyright:
© The Author(s) 2018.

Keywords

bilateral hearing loss
chronic myeloid leukemia
CML
sudden hearing loss
tinnitus
vertigo

ASJC Scopus subject areas

Otorhinolaryngology

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10.1177/0003489418787831

Cite this

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title = "Sudden Bilateral Hearing Loss, Tinnitus, and Vertigo as Presenting Symptoms of Chronic Myeloid Leukemia",

abstract = "Objectives: The objective was to describe a unique case of sudden bilateral hearing loss, tinnitus, and vertigo presenting as the first symptoms of chronic myeloid leukemia (CML). Methods: A patient case is discussed along with a review of associated literature. Results: A patient presented with sudden onset hearing loss, tinnitus, and vertigo, and was diagnosed with CML with an initial white blood cell (WBC) count of 555 000 per microliter. The proposed etiology of otologic symptoms is hyperleukocytosis. Serial audiograms showed minimal improvement in hearing despite reduction of WBC. Conclusion: In cases of bilateral, sudden onset sensorineural hearing loss, evaluation for systemic causes of otologic symptoms, including CML, should be considered.",

keywords = "bilateral hearing loss, chronic myeloid leukemia, CML, sudden hearing loss, tinnitus, vertigo",

author = "Cass, \{Nathan D.\} and Gubbels, \{Samuel P.\} and Portnuff, \{Cory D.F.\}",

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year = "2018",

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doi = "10.1177/0003489418787831",

language = "English",

volume = "127",

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T1 - Sudden Bilateral Hearing Loss, Tinnitus, and Vertigo as Presenting Symptoms of Chronic Myeloid Leukemia

AU - Cass, Nathan D.

AU - Gubbels, Samuel P.

AU - Portnuff, Cory D.F.

N1 - Publisher Copyright: © The Author(s) 2018.

PY - 2018/10/1

Y1 - 2018/10/1

N2 - Objectives: The objective was to describe a unique case of sudden bilateral hearing loss, tinnitus, and vertigo presenting as the first symptoms of chronic myeloid leukemia (CML). Methods: A patient case is discussed along with a review of associated literature. Results: A patient presented with sudden onset hearing loss, tinnitus, and vertigo, and was diagnosed with CML with an initial white blood cell (WBC) count of 555 000 per microliter. The proposed etiology of otologic symptoms is hyperleukocytosis. Serial audiograms showed minimal improvement in hearing despite reduction of WBC. Conclusion: In cases of bilateral, sudden onset sensorineural hearing loss, evaluation for systemic causes of otologic symptoms, including CML, should be considered.

AB - Objectives: The objective was to describe a unique case of sudden bilateral hearing loss, tinnitus, and vertigo presenting as the first symptoms of chronic myeloid leukemia (CML). Methods: A patient case is discussed along with a review of associated literature. Results: A patient presented with sudden onset hearing loss, tinnitus, and vertigo, and was diagnosed with CML with an initial white blood cell (WBC) count of 555 000 per microliter. The proposed etiology of otologic symptoms is hyperleukocytosis. Serial audiograms showed minimal improvement in hearing despite reduction of WBC. Conclusion: In cases of bilateral, sudden onset sensorineural hearing loss, evaluation for systemic causes of otologic symptoms, including CML, should be considered.

KW - bilateral hearing loss

KW - chronic myeloid leukemia

KW - CML

KW - sudden hearing loss

KW - tinnitus

KW - vertigo

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JO - Annals of Otology, Rhinology and Laryngology

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Sudden Bilateral Hearing Loss, Tinnitus, and Vertigo as Presenting Symptoms of Chronic Myeloid Leukemia

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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