Sulfated quaternary amine lipids: A new class of inverse charge zwitterlipids

Vincent J. Venditto; Aaron Dolor; Aditya Kohli; Stefan Salentinig; Ben J. Boyd; Francis C. Szok

doi:10.1039/c4cc02866j

Sulfated quaternary amine lipids: A new class of inverse charge zwitterlipids

Vincent J. Venditto, Aaron Dolor, Aditya Kohli, Stefan Salentinig, Ben J. Boyd, Francis C. Szok

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

We describe a new class of charge inverted zwitterionic sulfated lipids (AS) with a cationic quaternary amine anchored at the membrane interface and an anionic sulfate moiety extended into the aqueous phase. These lipids have exceptionally high transition temperatures and assemble into lipid aggregates when dispersed in aqueous solutions.

Original language	English
Pages (from-to)	9109-9111
Number of pages	3
Journal	Chemical Communications
Volume	50
Issue number	65
DOIs	https://doi.org/10.1039/c4cc02866j
State	Published - Jul 17 2014

Funding

Funders	Funder number
National Institute of General Medical Sciences DP2GM119177 Sophie Dumont National Institute of General Medical Sciences	T32GM007175

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Catalysis
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c4cc02866j

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title = "Sulfated quaternary amine lipids: A new class of inverse charge zwitterlipids",

abstract = "We describe a new class of charge inverted zwitterionic sulfated lipids (AS) with a cationic quaternary amine anchored at the membrane interface and an anionic sulfate moiety extended into the aqueous phase. These lipids have exceptionally high transition temperatures and assemble into lipid aggregates when dispersed in aqueous solutions.",

author = "Venditto, \{Vincent J.\} and Aaron Dolor and Aditya Kohli and Stefan Salentinig and Boyd, \{Ben J.\} and Szok, \{Francis C.\}",

year = "2014",

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doi = "10.1039/c4cc02866j",

language = "English",

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T1 - Sulfated quaternary amine lipids

T2 - A new class of inverse charge zwitterlipids

AU - Venditto, Vincent J.

AU - Dolor, Aaron

AU - Kohli, Aditya

AU - Salentinig, Stefan

AU - Boyd, Ben J.

AU - Szok, Francis C.

PY - 2014/7/17

Y1 - 2014/7/17

N2 - We describe a new class of charge inverted zwitterionic sulfated lipids (AS) with a cationic quaternary amine anchored at the membrane interface and an anionic sulfate moiety extended into the aqueous phase. These lipids have exceptionally high transition temperatures and assemble into lipid aggregates when dispersed in aqueous solutions.

AB - We describe a new class of charge inverted zwitterionic sulfated lipids (AS) with a cationic quaternary amine anchored at the membrane interface and an anionic sulfate moiety extended into the aqueous phase. These lipids have exceptionally high transition temperatures and assemble into lipid aggregates when dispersed in aqueous solutions.

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U2 - 10.1039/c4cc02866j

DO - 10.1039/c4cc02866j

M3 - Article

C2 - 24984814

AN - SCOPUS:84904567795

SN - 1359-7345

VL - 50

SP - 9109

EP - 9111

JO - Chemical Communications

JF - Chemical Communications

IS - 65

ER -

Sulfated quaternary amine lipids: A new class of inverse charge zwitterlipids

Abstract

Funding

ASJC Scopus subject areas

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