Summary from an international cancer seminar focused on human papillomavirus (HPV)-positive oropharynx cancer, convened by scientists at IARC and NCI

Aimée R. Kreimer; Anil K. Chaturvedi; Laia Alemany; Devasena Anantharaman; Freddie Bray; Mary Carrington; John Doorbar; Gypsyamber D'Souza; Carole Fakhry; Robert L. Ferris; Maura Gillison; D. Neil Hayes; Allan Hildesheim; Shao Hui Huang; Luiz P. Kowalski; Krystle A. Lang Kuhs; James Lewis; Douglas R. Lowy; Hisham Mehanna; Andy Ness; Michael Pawlita; Maisa Pinheiro; John Schiller; Meredith S. Shiels; Joseph Tota; Lisa Mirabello; Saman Warnakulasuriya; Tim Waterboer; William Westra; Stephen Chanock; Paul Brennan

doi:10.1016/j.oraloncology.2020.104736

Summary from an international cancer seminar focused on human papillomavirus (HPV)-positive oropharynx cancer, convened by scientists at IARC and NCI

Aimée R. Kreimer, Anil K. Chaturvedi, Laia Alemany, Devasena Anantharaman, Freddie Bray, Mary Carrington, John Doorbar, Gypsyamber D'Souza, Carole Fakhry, Robert L. Ferris, Maura Gillison, D. Neil Hayes, Allan Hildesheim, Shao Hui Huang, Luiz P. Kowalski, Krystle A. Lang Kuhs, James Lewis, Douglas R. Lowy, Hisham Mehanna, Andy NessMichael Pawlita, Maisa Pinheiro, John Schiller, Meredith S. Shiels, Joseph Tota, Lisa Mirabello, Saman Warnakulasuriya, Tim Waterboer, William Westra, Stephen Chanock, Paul Brennan

Research output: Contribution to journal › Short survey › peer-review

31 Scopus citations

Abstract

Cancer of the oropharynx has attracted considerable attention in recent years given: (1) an increasing incidence in selected populations over the past three decades; (2) the discovery of human papillomavirus (HPV) infection as the driver of the increase, as opposed to the traditional risk factors such as tobacco (smoking and chewing) and alcohol; and (3) the promise of new prevention and treatment strategies. As a result of such developments, the International Agency for Research on Cancer (IARC) and the US National Cancer Institute (NCI), convened the fourth Cancer Seminar meeting in November 2018 to focus on this topic. This report summarizes the proceedings: a review of recent science on the descriptive epidemiology, etiology, biology, genetics, early detection, pathology and treatment of HPV-positive oropharyngeal cancer, and the formulation of key research questions to be addressed.

Original language	English
Article number	104736
Journal	Oral Oncology
Volume	108
DOIs	https://doi.org/10.1016/j.oraloncology.2020.104736
State	Published - Sep 2020

Bibliographical note

Funding Information:
The meeting was funded jointly by the International Agency for Research on Cancer (IARC) and the Division of Cancer Epidemiology and Genetics (DCEG) of the US National Cancer Institute Intramural Research Program (no grant number applicable).

Funding Information:
The authors thank Ms. Betty Yu for her assistance organizing the meeting and Dr. M?nica S. Sierra for her assistance in finalizing manuscript. Where authors are identified as personnel of the International Agency for Research on Cancer / World Health Organization, the authors alone are responsible for the views expressed in this article and they do not necessarily represent the decisions, policy or views of the International Agency for Research on Cancer / World Health Organization.

Publisher Copyright:
© 2020

Keywords

Etiology
Genetics
HPV
Oropharynx cancer
Prevention
Screening
Therapy

ASJC Scopus subject areas

Oral Surgery
Oncology
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.oraloncology.2020.104736

Cite this

Kreimer, A. R., Chaturvedi, A. K., Alemany, L., Anantharaman, D., Bray, F., Carrington, M., Doorbar, J., D'Souza, G., Fakhry, C., Ferris, R. L., Gillison, M., Neil Hayes, D., Hildesheim, A., Huang, S. H., Kowalski, L. P., Lang Kuhs, K. A., Lewis, J., Lowy, D. R., Mehanna, H., ... Brennan, P. (2020). Summary from an international cancer seminar focused on human papillomavirus (HPV)-positive oropharynx cancer, convened by scientists at IARC and NCI. Oral Oncology, 108, [104736]. https://doi.org/10.1016/j.oraloncology.2020.104736

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abstract = "Cancer of the oropharynx has attracted considerable attention in recent years given: (1) an increasing incidence in selected populations over the past three decades; (2) the discovery of human papillomavirus (HPV) infection as the driver of the increase, as opposed to the traditional risk factors such as tobacco (smoking and chewing) and alcohol; and (3) the promise of new prevention and treatment strategies. As a result of such developments, the International Agency for Research on Cancer (IARC) and the US National Cancer Institute (NCI), convened the fourth Cancer Seminar meeting in November 2018 to focus on this topic. This report summarizes the proceedings: a review of recent science on the descriptive epidemiology, etiology, biology, genetics, early detection, pathology and treatment of HPV-positive oropharyngeal cancer, and the formulation of key research questions to be addressed.",

keywords = "Etiology, Genetics, HPV, Oropharynx cancer, Prevention, Screening, Therapy",

author = "Kreimer, {Aim{\'e}e R.} and Chaturvedi, {Anil K.} and Laia Alemany and Devasena Anantharaman and Freddie Bray and Mary Carrington and John Doorbar and Gypsyamber D'Souza and Carole Fakhry and Ferris, {Robert L.} and Maura Gillison and {Neil Hayes}, D. and Allan Hildesheim and Huang, {Shao Hui} and Kowalski, {Luiz P.} and {Lang Kuhs}, {Krystle A.} and James Lewis and Lowy, {Douglas R.} and Hisham Mehanna and Andy Ness and Michael Pawlita and Maisa Pinheiro and John Schiller and Shiels, {Meredith S.} and Joseph Tota and Lisa Mirabello and Saman Warnakulasuriya and Tim Waterboer and William Westra and Stephen Chanock and Paul Brennan",

note = "Funding Information: The meeting was funded jointly by the International Agency for Research on Cancer (IARC) and the Division of Cancer Epidemiology and Genetics (DCEG) of the US National Cancer Institute Intramural Research Program (no grant number applicable). Funding Information: The authors thank Ms. Betty Yu for her assistance organizing the meeting and Dr. M?nica S. Sierra for her assistance in finalizing manuscript. Where authors are identified as personnel of the International Agency for Research on Cancer / World Health Organization, the authors alone are responsible for the views expressed in this article and they do not necessarily represent the decisions, policy or views of the International Agency for Research on Cancer / World Health Organization. Publisher Copyright: {\textcopyright} 2020",

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month = sep,

doi = "10.1016/j.oraloncology.2020.104736",

language = "English",

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Kreimer, AR, Chaturvedi, AK, Alemany, L, Anantharaman, D, Bray, F, Carrington, M, Doorbar, J, D'Souza, G, Fakhry, C, Ferris, RL, Gillison, M, Neil Hayes, D, Hildesheim, A, Huang, SH, Kowalski, LP, Lang Kuhs, KA, Lewis, J, Lowy, DR, Mehanna, H, Ness, A, Pawlita, M, Pinheiro, M, Schiller, J, Shiels, MS, Tota, J, Mirabello, L, Warnakulasuriya, S, Waterboer, T, Westra, W, Chanock, S & Brennan, P 2020, 'Summary from an international cancer seminar focused on human papillomavirus (HPV)-positive oropharynx cancer, convened by scientists at IARC and NCI', Oral Oncology, vol. 108, 104736. https://doi.org/10.1016/j.oraloncology.2020.104736

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T1 - Summary from an international cancer seminar focused on human papillomavirus (HPV)-positive oropharynx cancer, convened by scientists at IARC and NCI

AU - Kreimer, Aimée R.

AU - Chaturvedi, Anil K.

AU - Alemany, Laia

AU - Anantharaman, Devasena

AU - Bray, Freddie

AU - Carrington, Mary

AU - Doorbar, John

AU - D'Souza, Gypsyamber

AU - Fakhry, Carole

AU - Ferris, Robert L.

AU - Gillison, Maura

AU - Neil Hayes, D.

AU - Hildesheim, Allan

AU - Huang, Shao Hui

AU - Kowalski, Luiz P.

AU - Lang Kuhs, Krystle A.

AU - Lewis, James

AU - Lowy, Douglas R.

AU - Mehanna, Hisham

AU - Ness, Andy

AU - Pawlita, Michael

AU - Pinheiro, Maisa

AU - Schiller, John

AU - Shiels, Meredith S.

AU - Tota, Joseph

AU - Mirabello, Lisa

AU - Warnakulasuriya, Saman

AU - Waterboer, Tim

AU - Westra, William

AU - Chanock, Stephen

AU - Brennan, Paul

N1 - Funding Information: The meeting was funded jointly by the International Agency for Research on Cancer (IARC) and the Division of Cancer Epidemiology and Genetics (DCEG) of the US National Cancer Institute Intramural Research Program (no grant number applicable). Funding Information: The authors thank Ms. Betty Yu for her assistance organizing the meeting and Dr. M?nica S. Sierra for her assistance in finalizing manuscript. Where authors are identified as personnel of the International Agency for Research on Cancer / World Health Organization, the authors alone are responsible for the views expressed in this article and they do not necessarily represent the decisions, policy or views of the International Agency for Research on Cancer / World Health Organization. Publisher Copyright: © 2020

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N2 - Cancer of the oropharynx has attracted considerable attention in recent years given: (1) an increasing incidence in selected populations over the past three decades; (2) the discovery of human papillomavirus (HPV) infection as the driver of the increase, as opposed to the traditional risk factors such as tobacco (smoking and chewing) and alcohol; and (3) the promise of new prevention and treatment strategies. As a result of such developments, the International Agency for Research on Cancer (IARC) and the US National Cancer Institute (NCI), convened the fourth Cancer Seminar meeting in November 2018 to focus on this topic. This report summarizes the proceedings: a review of recent science on the descriptive epidemiology, etiology, biology, genetics, early detection, pathology and treatment of HPV-positive oropharyngeal cancer, and the formulation of key research questions to be addressed.

AB - Cancer of the oropharynx has attracted considerable attention in recent years given: (1) an increasing incidence in selected populations over the past three decades; (2) the discovery of human papillomavirus (HPV) infection as the driver of the increase, as opposed to the traditional risk factors such as tobacco (smoking and chewing) and alcohol; and (3) the promise of new prevention and treatment strategies. As a result of such developments, the International Agency for Research on Cancer (IARC) and the US National Cancer Institute (NCI), convened the fourth Cancer Seminar meeting in November 2018 to focus on this topic. This report summarizes the proceedings: a review of recent science on the descriptive epidemiology, etiology, biology, genetics, early detection, pathology and treatment of HPV-positive oropharyngeal cancer, and the formulation of key research questions to be addressed.

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KW - Genetics

KW - HPV

KW - Oropharynx cancer

KW - Prevention

KW - Screening

KW - Therapy

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ER -

Summary from an international cancer seminar focused on human papillomavirus (HPV)-positive oropharynx cancer, convened by scientists at IARC and NCI

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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