TY - JOUR
T1 - Suppression of Shivering Decreases Oxygen Consumption and Improves Hemodynamic Stability during Postoperative Rewarming
AU - Zwischenberger, J. B.
AU - Kirsh, M. M.
AU - Dechert, R. E.
AU - Arnold, D. K.
AU - Bartlett, R. H.
PY - 1987
Y1 - 1987
N2 - Thirty-three patients undergoing elective myocardial revascularization were prospectively randomized into two study groups (Group S and Group P) to permit evaluation of the effects of shivering on oxygen consumption per minute (Vo2), carbon dioxide production per minute (Vco2), and hemodynamic performance. Group S was allowed to shiver during the postoperative rewarming period, and Group P received hourly injections of pancuronium bromide and Metubine (metocurine) sulfate with sedation to block the shivering response. Group S demonstrated significantly higher increases in Vo2 and Vco2, lower systolic blood pressure and mixed venous oxygen saturation, and a greater use of inotropic support than the patients in Group P. Suppression of the shivering response minimized increases in Vo2 and Vco2, improved hemodynamic stability, and resulted in a decreased need for inotropic support.
AB - Thirty-three patients undergoing elective myocardial revascularization were prospectively randomized into two study groups (Group S and Group P) to permit evaluation of the effects of shivering on oxygen consumption per minute (Vo2), carbon dioxide production per minute (Vco2), and hemodynamic performance. Group S was allowed to shiver during the postoperative rewarming period, and Group P received hourly injections of pancuronium bromide and Metubine (metocurine) sulfate with sedation to block the shivering response. Group S demonstrated significantly higher increases in Vo2 and Vco2, lower systolic blood pressure and mixed venous oxygen saturation, and a greater use of inotropic support than the patients in Group P. Suppression of the shivering response minimized increases in Vo2 and Vco2, improved hemodynamic stability, and resulted in a decreased need for inotropic support.
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U2 - 10.1016/S0003-4975(10)62823-8
DO - 10.1016/S0003-4975(10)62823-8
M3 - Article
C2 - 3105477
AN - SCOPUS:0023145897
SN - 0003-4975
VL - 43
SP - 428
EP - 431
JO - Annals of Thoracic Surgery
JF - Annals of Thoracic Surgery
IS - 4
ER -