Suppression of Shivering Decreases Oxygen Consumption and Improves Hemodynamic Stability during Postoperative Rewarming

J. B. Zwischenberger, M. M. Kirsh, R. E. Dechert, D. K. Arnold, R. H. Bartlett

Research output: Contribution to journalArticlepeer-review

72 Scopus citations

Abstract

Thirty-three patients undergoing elective myocardial revascularization were prospectively randomized into two study groups (Group S and Group P) to permit evaluation of the effects of shivering on oxygen consumption per minute (Vo2), carbon dioxide production per minute (Vco2), and hemodynamic performance. Group S was allowed to shiver during the postoperative rewarming period, and Group P received hourly injections of pancuronium bromide and Metubine (metocurine) sulfate with sedation to block the shivering response. Group S demonstrated significantly higher increases in Vo2 and Vco2, lower systolic blood pressure and mixed venous oxygen saturation, and a greater use of inotropic support than the patients in Group P. Suppression of the shivering response minimized increases in Vo2 and Vco2, improved hemodynamic stability, and resulted in a decreased need for inotropic support.

Original languageEnglish
Pages (from-to)428-431
Number of pages4
JournalAnnals of Thoracic Surgery
Volume43
Issue number4
DOIs
StatePublished - 1987

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

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