To the Editor: Patchell et al. (Feb. 22 issue)1 report that surgical resection followed by whole-brain radiation therapy for single brain metastasis prolongs overall survival and functional independence and reduces the risk of local recurrence as compared with radiation therapy alone. These are important observations. However, before every patient with a single accessible brain metastasis is offered surgery, several points need clarification. We ask Patchell et al. to comment on the mechanism by which their patients were ascertained and to reassure us that they are representative of all patients who have single accessible brain metastases. Referral patterns, criteria for entry.
|Number of pages||2|
|Journal||New England Journal of Medicine|
|State||Published - Jul 12 1990|
ASJC Scopus subject areas
- Medicine (all)