Surgery for single brain metastasis

David R. Macdonald, J. Gregory Cairncross, Roy A. Patchell, Phillip A. Tibbs, John W. Walsh, Robert J. Dempsey, Yosh Maruyama, Richard J. Kryscio, William R. Markesbery, John S. Macdonald, Byron Young

Research output: Contribution to journalLetterpeer-review

8 Scopus citations


To the Editor: Patchell et al. (Feb. 22 issue)1 report that surgical resection followed by whole-brain radiation therapy for single brain metastasis prolongs overall survival and functional independence and reduces the risk of local recurrence as compared with radiation therapy alone. These are important observations. However, before every patient with a single accessible brain metastasis is offered surgery, several points need clarification. We ask Patchell et al. to comment on the mechanism by which their patients were ascertained and to reassure us that they are representative of all patients who have single accessible brain metastases. Referral patterns, criteria for entry.

Original languageEnglish
Pages (from-to)132-133
Number of pages2
JournalNew England Journal of Medicine
Issue number2
StatePublished - Jul 12 1990

ASJC Scopus subject areas

  • Medicine (all)


Dive into the research topics of 'Surgery for single brain metastasis'. Together they form a unique fingerprint.

Cite this