TY - JOUR
T1 - Surgery for single brain metastasis
AU - Macdonald, David R.
AU - Cairncross, J. Gregory
AU - Patchell, Roy A.
AU - Tibbs, Phillip A.
AU - Walsh, John W.
AU - Dempsey, Robert J.
AU - Maruyama, Yosh
AU - Kryscio, Richard J.
AU - Markesbery, William R.
AU - Macdonald, John S.
AU - Young, Byron
PY - 1990/7/12
Y1 - 1990/7/12
N2 - To the Editor: Patchell et al. (Feb. 22 issue)1 report that surgical resection followed by whole-brain radiation therapy for single brain metastasis prolongs overall survival and functional independence and reduces the risk of local recurrence as compared with radiation therapy alone. These are important observations. However, before every patient with a single accessible brain metastasis is offered surgery, several points need clarification. We ask Patchell et al. to comment on the mechanism by which their patients were ascertained and to reassure us that they are representative of all patients who have single accessible brain metastases. Referral patterns, criteria for entry.
AB - To the Editor: Patchell et al. (Feb. 22 issue)1 report that surgical resection followed by whole-brain radiation therapy for single brain metastasis prolongs overall survival and functional independence and reduces the risk of local recurrence as compared with radiation therapy alone. These are important observations. However, before every patient with a single accessible brain metastasis is offered surgery, several points need clarification. We ask Patchell et al. to comment on the mechanism by which their patients were ascertained and to reassure us that they are representative of all patients who have single accessible brain metastases. Referral patterns, criteria for entry.
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U2 - 10.1056/NEJM199007123230214
DO - 10.1056/NEJM199007123230214
M3 - Letter
C2 - 2359423
AN - SCOPUS:0025706044
SN - 0028-4793
VL - 323
SP - 132
EP - 133
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 2
ER -