Surgical Management of Adrenocortical Carcinoma

Gustavo G. Fernandez Ranvier; William B. Inabnet

doi:10.1016/j.ecl.2015.02.008

Surgical Management of Adrenocortical Carcinoma

Gustavo G. Fernandez Ranvier, William B. Inabnet

Research output: Contribution to journal › Review article › peer-review

18 Citations (SciVal)

Abstract

Adrenocortical carcinoma (ACC) is rare but one of the most malignant endocrine tumors. This article reviews and summarizes the current knowledge about the treatment of ACC. The epidemiology and molecular events involved in the pathogenesis of ACC are briefly outlined. The different diagnostic tools to distinguish benign from malignant adrenocortical tumors, including biochemical analysis and imaging, are discussed. The surgical treatment of ACC has evolved in the last 2 decades. The different surgical alternatives for the treatment of ACC in the context of primary, recurrent, or metastatic disease are reviewed, and the remaining challenges and controversies are discussed.

Original language	English
Pages (from-to)	435-452
Number of pages	18
Journal	Endocrinology and Metabolism Clinics of North America
Volume	44
Issue number	2
DOIs	https://doi.org/10.1016/j.ecl.2015.02.008
State	Published - Jun 1 2015

Bibliographical note

Publisher Copyright:
© 2015 Elsevier Inc.

Keywords

Adrenocortical carcinoma
Adrenocortical tumor
Chemotherapy for adrenocortical carcinoma
Metastatic adrenocortical carcinoma
Mitotane treatment
Open adrenalectomy

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Endocrinology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.ecl.2015.02.008

Cite this

@article{e09a76927b1a4f5dbbaa651aff6efa23,

title = "Surgical Management of Adrenocortical Carcinoma",

abstract = "Adrenocortical carcinoma (ACC) is rare but one of the most malignant endocrine tumors. This article reviews and summarizes the current knowledge about the treatment of ACC. The epidemiology and molecular events involved in the pathogenesis of ACC are briefly outlined. The different diagnostic tools to distinguish benign from malignant adrenocortical tumors, including biochemical analysis and imaging, are discussed. The surgical treatment of ACC has evolved in the last 2 decades. The different surgical alternatives for the treatment of ACC in the context of primary, recurrent, or metastatic disease are reviewed, and the remaining challenges and controversies are discussed.",

keywords = "Adrenocortical carcinoma, Adrenocortical tumor, Chemotherapy for adrenocortical carcinoma, Metastatic adrenocortical carcinoma, Mitotane treatment, Open adrenalectomy",

author = "{Fernandez Ranvier}, {Gustavo G.} and Inabnet, {William B.}",

note = "Publisher Copyright: {\textcopyright} 2015 Elsevier Inc.",

year = "2015",

month = jun,

day = "1",

doi = "10.1016/j.ecl.2015.02.008",

language = "English",

volume = "44",

pages = "435--452",

number = "2",

}

TY - JOUR

T1 - Surgical Management of Adrenocortical Carcinoma

AU - Fernandez Ranvier, Gustavo G.

AU - Inabnet, William B.

PY - 2015/6/1

Y1 - 2015/6/1

N2 - Adrenocortical carcinoma (ACC) is rare but one of the most malignant endocrine tumors. This article reviews and summarizes the current knowledge about the treatment of ACC. The epidemiology and molecular events involved in the pathogenesis of ACC are briefly outlined. The different diagnostic tools to distinguish benign from malignant adrenocortical tumors, including biochemical analysis and imaging, are discussed. The surgical treatment of ACC has evolved in the last 2 decades. The different surgical alternatives for the treatment of ACC in the context of primary, recurrent, or metastatic disease are reviewed, and the remaining challenges and controversies are discussed.

AB - Adrenocortical carcinoma (ACC) is rare but one of the most malignant endocrine tumors. This article reviews and summarizes the current knowledge about the treatment of ACC. The epidemiology and molecular events involved in the pathogenesis of ACC are briefly outlined. The different diagnostic tools to distinguish benign from malignant adrenocortical tumors, including biochemical analysis and imaging, are discussed. The surgical treatment of ACC has evolved in the last 2 decades. The different surgical alternatives for the treatment of ACC in the context of primary, recurrent, or metastatic disease are reviewed, and the remaining challenges and controversies are discussed.

KW - Adrenocortical carcinoma

KW - Adrenocortical tumor

KW - Chemotherapy for adrenocortical carcinoma

KW - Metastatic adrenocortical carcinoma

KW - Mitotane treatment

KW - Open adrenalectomy

UR - http://www.scopus.com/inward/record.url?scp=84930381034&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84930381034&partnerID=8YFLogxK

U2 - 10.1016/j.ecl.2015.02.008

DO - 10.1016/j.ecl.2015.02.008

M3 - Review article

C2 - 26038210

AN - SCOPUS:84930381034

SN - 0889-8529

VL - 44

SP - 435

EP - 452

JO - Endocrinology and Metabolism Clinics of North America

JF - Endocrinology and Metabolism Clinics of North America

IS - 2

ER -

Surgical Management of Adrenocortical Carcinoma

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this