Susceptibility of livestock and companion animals to COVID-19

Chithra C. Sreenivasan, Milton Thomas, Dan Wang, Feng Li

Research output: Contribution to journalReview articlepeer-review

16 Scopus citations


While the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to wreak havoc, there is little known about the susceptibility of the livestock and companion animals relative to humans. Here, we explore the susceptibility of companion and agricultural animals, in light of the existing information on natural infections, experimental infections, serosurveillance, and in vitro protein-homology binding interaction studies of the SARS-CoV-2 with the proposed receptor angiotensin-converting enzyme 2 from diverse animal species.

Original languageEnglish
Pages (from-to)1351-1360
Number of pages10
JournalJournal of Medical Virology
Issue number3
StatePublished - Mar 2021

Bibliographical note

Funding Information:
The authors would like to thank the members of the Feng Li and Dan Wang laboratory for helpful discussion and critical review of the manuscript. The authors also thank the support provided by the William Robert Mills Chair Endowment Fund and Agricultural Experiment Station of the University of Kentucky.

Publisher Copyright:
© 2020 Wiley Periodicals LLC


  • COVID-19
  • SARS-CoV-2
  • animals
  • companion
  • livestock
  • pets
  • reverse zoonosis
  • susceptibility
  • transmission
  • zoonosis

ASJC Scopus subject areas

  • Virology
  • Infectious Diseases


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