Symmetrical dinuclear complexes with high DNA affinity based on [Ru(dpq)2(phen)]2+

Janice Aldrich-Wright; Craig Brodie; Edith C. Glazer; Nathan W. Luedtke; Lev Elson-Schwab; Yitzhak Tor

doi:10.1039/b316917k

Symmetrical dinuclear complexes with high DNA affinity based on [Ru(dpq)₂(phen)]²⁺

Janice Aldrich-Wright, Craig Brodie, Edith C. Glazer, Nathan W. Luedtke, Lev Elson-Schwab, Yitzhak Tor

Chemistry

Research output: Contribution to journal › Article › peer-review

50 Scopus citations

Abstract

Symmetrical homometallic dinuclear complexes of the type [(Ru(dpq)₂)₂(phen–SOS–phen)]⁴⁺, with a flexible 2-mercaptoethyl ether linker joining the two [Ru(dpq)₂(phen)]²⁺-based sub-units, have DNA dissociation constants (K _d) in the nM range.

Original language	English
Pages (from-to)	1018-1019
Number of pages	2
Journal	Chemical Communications
Volume	4
Issue number	8
DOIs	https://doi.org/10.1039/b316917k
State	Published - 2004

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Catalysis
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/b316917k

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title = "Symmetrical dinuclear complexes with high DNA affinity based on [Ru(dpq)2(phen)]2+",

abstract = "Symmetrical homometallic dinuclear complexes of the type [(Ru(dpq)2)2(phen–SOS–phen)]4+, with a flexible 2-mercaptoethyl ether linker joining the two [Ru(dpq)2(phen)]2+-based sub-units, have DNA dissociation constants (K d) in the nM range.",

author = "Janice Aldrich-Wright and Craig Brodie and Glazer, {Edith C.} and Luedtke, {Nathan W.} and Lev Elson-Schwab and Yitzhak Tor",

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T1 - Symmetrical dinuclear complexes with high DNA affinity based on [Ru(dpq)2(phen)]2+

AU - Aldrich-Wright, Janice

AU - Brodie, Craig

AU - Glazer, Edith C.

AU - Luedtke, Nathan W.

AU - Elson-Schwab, Lev

AU - Tor, Yitzhak

PY - 2004

Y1 - 2004

N2 - Symmetrical homometallic dinuclear complexes of the type [(Ru(dpq)2)2(phen–SOS–phen)]4+, with a flexible 2-mercaptoethyl ether linker joining the two [Ru(dpq)2(phen)]2+-based sub-units, have DNA dissociation constants (K d) in the nM range.

AB - Symmetrical homometallic dinuclear complexes of the type [(Ru(dpq)2)2(phen–SOS–phen)]4+, with a flexible 2-mercaptoethyl ether linker joining the two [Ru(dpq)2(phen)]2+-based sub-units, have DNA dissociation constants (K d) in the nM range.

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U2 - 10.1039/b316917k

DO - 10.1039/b316917k

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JO - Chemical Communications

JF - Chemical Communications

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ER -

Symmetrical dinuclear complexes with high DNA affinity based on [Ru(dpq)₂(phen)]²⁺

Abstract

ASJC Scopus subject areas

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