Symmetrical dinuclear complexes with high DNA affinity based on [Ru(dpq)2(phen)]2+

Janice Aldrich-Wright, Craig Brodie, Edith C. Glazer, Nathan W. Luedtke, Lev Elson-Schwab, Yitzhak Tor

Research output: Contribution to journalArticlepeer-review

48 Scopus citations

Abstract

Symmetrical homometallic dinuclear complexes of the type [(Ru(dpq)2)2(phen–SOS–phen)]4+, with a flexible 2-mercaptoethyl ether linker joining the two [Ru(dpq)2(phen)]2+-based sub-units, have DNA dissociation constants (K d) in the nM range.

Original languageEnglish
Pages (from-to)1018-1019
Number of pages2
JournalChemical Communications
Volume4
Issue number8
DOIs
StatePublished - 2004

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry (all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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