Synthesis of symmetrical 1,5-disubstituted granatanines

Ashish P. Vartak, Linda P. Dwoskin, Peter A. Crooks

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


A general entry into symmetrical 1,5-disubstituted granatanines that involves an alkylative ring-closure on a 2,6-bis enolate piperidine intermediate is described.

Original languageEnglish
Pages (from-to)6330-6333
Number of pages4
JournalTetrahedron Letters
Issue number44
StatePublished - Oct 27 2008

Bibliographical note

Funding Information:
This work was supported by the National Institutes of Health, NIDA Grant 013519.

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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