Synthesis of symmetrical 1,5-disubstituted granatanines

Ashish P. Vartak; Linda P. Dwoskin; Peter A. Crooks

doi:10.1016/j.tetlet.2008.08.066

Synthesis of symmetrical 1,5-disubstituted granatanines

Ashish P. Vartak
, Linda P. Dwoskin
, Peter A. Crooks

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

A general entry into symmetrical 1,5-disubstituted granatanines that involves an alkylative ring-closure on a 2,6-bis enolate piperidine intermediate is described.

Original language	English
Pages (from-to)	6330-6333
Number of pages	4
Journal	Tetrahedron Letters
Volume	49
Issue number	44
DOIs	https://doi.org/10.1016/j.tetlet.2008.08.066
State	Published - Oct 27 2008

Bibliographical note

Funding Information:
This work was supported by the National Institutes of Health, NIDA Grant 013519.

Funding

This work was supported by the National Institutes of Health, NIDA Grant 013519.

Funders	Funder number
National Institutes of Health (NIH)
National Institute of Development Administration	013519
National Institute of Development Administration

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tetlet.2008.08.066

Cite this

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title = "Synthesis of symmetrical 1,5-disubstituted granatanines",

abstract = "A general entry into symmetrical 1,5-disubstituted granatanines that involves an alkylative ring-closure on a 2,6-bis enolate piperidine intermediate is described.",

author = "Vartak, \{Ashish P.\} and Dwoskin, \{Linda P.\} and Crooks, \{Peter A.\}",

note = "Funding Information: This work was supported by the National Institutes of Health, NIDA Grant 013519. ",

year = "2008",

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doi = "10.1016/j.tetlet.2008.08.066",

language = "English",

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T1 - Synthesis of symmetrical 1,5-disubstituted granatanines

AU - Vartak, Ashish P.

AU - Dwoskin, Linda P.

AU - Crooks, Peter A.

N1 - Funding Information: This work was supported by the National Institutes of Health, NIDA Grant 013519.

PY - 2008/10/27

Y1 - 2008/10/27

N2 - A general entry into symmetrical 1,5-disubstituted granatanines that involves an alkylative ring-closure on a 2,6-bis enolate piperidine intermediate is described.

AB - A general entry into symmetrical 1,5-disubstituted granatanines that involves an alkylative ring-closure on a 2,6-bis enolate piperidine intermediate is described.

UR - https://www.scopus.com/pages/publications/51549109900

UR - https://www.scopus.com/pages/publications/51549109900#tab=citedBy

U2 - 10.1016/j.tetlet.2008.08.066

DO - 10.1016/j.tetlet.2008.08.066

M3 - Article

AN - SCOPUS:51549109900

SN - 0040-4039

VL - 49

SP - 6330

EP - 6333

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 44

ER -

Synthesis of symmetrical 1,5-disubstituted granatanines

Abstract

Bibliographical note

Funding

ASJC Scopus subject areas

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