Temperature during coronary artery bypass surgery affects quality of life

Parinda Khatri, Michael Babyak, Narda D. Croughwell, Rebecca Davis, William D. White, Mark F. Newman, Joseph G. Reves, Daniel B. Mark, James A. Blumenthal

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


Background. The objective of this study was to examine the effects of temperature on a variety of indices of psychologic adjustment and quality of life. Methods. A total of 209 patients randomly received normothermic (warm) or hypothermic (cold) conditions during coronary artery bypass surgery (CABS), and a number of physical, social, and psychologic measures were assessed before as well as 6 weeks and 6 months after CABS. Results. Repeated measures analyses of covariance revealed significant temperature group main effects for anxiety (p = 0.008) and depression (p = 0.039), with the normothermic group obtaining lower anxiety and depression levels than the hypothermic group at both 6 weeks and 6 months after surgery. Additionally, among patients who entered the study with higher depression levels, those in the hypothermic group tended to have higher depression scores at follow-up compared with patients in the normothermic condition (p = 0.012). No temperature group differences were observed on other quality of life indices. Conclusions. The results of the present study indicate that hypothermic conditions during CABS are associated with higher levels of emotional distress after CABS than normothermic conditions, particularly for patients with greater stress to begin with.

Original languageEnglish
Pages (from-to)110-116
Number of pages7
JournalAnnals of Thoracic Surgery
Issue number1
StatePublished - 2001

Bibliographical note

Funding Information:
The preparation of this article was supported, in part, by National Institutes of Health grants HL49572, 49678, AG09663, MH49679, and HL59672.

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine


Dive into the research topics of 'Temperature during coronary artery bypass surgery affects quality of life'. Together they form a unique fingerprint.

Cite this