The 2008 update of the Aspergillus nidulans genome annotation: a community effort.

Jennifer Russo Wortman, Jane Mabey Gilsenan, Vinita Joardar, Jennifer Deegan, John Clutterbuck, Mikael R. Andersen, David Archer, Mojca Bencina, Gerhard Braus, Pedro Coutinho, Hans von Döhren, John Doonan, Arnold J.M. Driessen, Pawel Durek, Eduardo Espeso, Erzsébet Fekete, Michel Flipphi, Carlos Garcia Estrada, Steven Geysens, Gustavo GoldmanPiet W.J. de Groot, Kim Hansen, Steven D. Harris, Thorsten Heinekamp, Kerstin Helmstaedt, Bernard Henrissat, Gerald Hofmann, Tim Homan, Tetsuya Horio, Hiroyuki Horiuchi, Steve James, Meriel Jones, Levente Karaffa, Zsolt Karányi, Masashi Kato, Nancy Keller, Diane E. Kelly, Jan A.K.W. Kiel, Jung Mi Kim, Ida J. van der Klei, Frans M. Klis, Andriy Kovalchuk, Nada Krasevec, Christian P. Kubicek, B. Liu, Andrew Maccabe, Vera Meyer, Pete Mirabito, Márton Miskei, Magdalena Mos, Jonathan Mullins, David R. Nelson, Jens Nielsen, Berl R. Oakley, Stephen A. Osmani, Tiina Pakula, Andrzej Paszewski, Ian Paulsen, Sebastian Pilsyk, István Pócsi, Peter J. Punt, Arthur F.J. Ram, Qinghu Ren, Xavier Robellet, Geoff Robson, Bernhard Seiboth, Piet van Solingen, Thomas Specht, Jibin Sun, Naimeh Taheri-Talesh, Norio Takeshita, Dave Ussery, Patricia A. vanKuyk, Hans Visser, Peter J.I. van de Vondervoort, Ronald P. de Vries, Jonathan Walton, Xin Xiang, Y. Xiong, An Ping Zeng, Bernd W. Brandt, Michael J. Cornell, Cees A.M.J.J. van den Hondel, Jacob Visser, Stephen G. Oliver, Geoffrey Turner

Research output: Contribution to journalArticlepeer-review

87 Scopus citations

Abstract

The identification and annotation of protein-coding genes is one of the primary goals of whole-genome sequencing projects, and the accuracy of predicting the primary protein products of gene expression is vital to the interpretation of the available data and the design of downstream functional applications. Nevertheless, the comprehensive annotation of eukaryotic genomes remains a considerable challenge. Many genomes submitted to public databases, including those of major model organisms, contain significant numbers of wrong and incomplete gene predictions. We present a community-based reannotation of the Aspergillus nidulans genome with the primary goal of increasing the number and quality of protein functional assignments through the careful review of experts in the field of fungal biology.

Original languageEnglish
Pages (from-to)S2-13
JournalFungal Genetics and Biology
Volume46 Suppl 1
DOIs
StatePublished - Mar 2009

Bibliographical note

Funding Information:
We acknowledge financial support by the European Commission under contract LSSG-CT-2005-018964. MC, and the use of the e-Fungi data warehouse, was supported by a grant to SGO and others as part of the BBSRC’s Bioinformatics and e-Science programme II. We wish to thank Dr Michael Anderson for his input on the assembly, whilst at The University of Manchester. We also acknowledge Todd Creasy for Manatee set-up and support, currently at IGS; Brian Haas for data management and computational support (annotation), currently at the Broad; Joshua Orvis for data management and computational support (annotation), currently at IGS; Jonathan Crabtree for data management and computational support (orthologues), currently at IGS. Sandra M.J. Langeveld is acknowledged for her assistance in preparing part of the manuscript.

ASJC Scopus subject areas

  • Microbiology
  • Genetics

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